Blocking immune cells’ path into brain limits neurodegeneration
In a mouse study, WashU Medicine researchers show that a drug injected into the body can reduce damage caused by a protein called tau, which accumulates in the brain in Alzheimer’s and related neurological diseases.
Brain activity varies with age in children with autistic traits
WashU Medicine researchers find that children with more autistic traits favored a brain activity pattern tied to sight and movement before age 9 and one tied to social and emotional processing after 14, suggesting interventions could be tailored by age.
Frequent cannabis use tied to more severe epilepsy
A study led by WashU Medicine researchers found that near-daily cannabis users with drug-resistant epilepsy had over twice as many convulsive seizures as nonusers, and they became resistant to antiseizure medications faster.
Blood proteins reveal effects of Alzheimer’s drug
WashU Medicine researchers found that dozens of blood proteins shifted during treatment with the anti-amyloid medication lecanemab, which could enable future blood tests monitoring a person’s response to the drug.
Advice from the frontline of alpha-gal syndrome
WashU Medicine allergist and immunologist Maya Jerath, MD, PhD, has treated over 650 patients with alpha-gal, a potentially life-threatening allergic reaction triggered by tick bites — and the prevalence is increasing rapidly, she says.
New Transcend Initiative to address mycobacteria threats
A new Transcend Initiative seeks to address and fight life-threatening mycobacterial infections.
Gut microbiome features predict devastating disease affecting preemies
WashU Medicine researchers found that bacteria-infecting viruses and bacterial antibiotic resistance genes in the gut microbiomes of premature babies play an important role in necrotizing enterocolitis, a sudden and often fatal intestinal illness.
Holtzman receives Landis Award for Outstanding Mentorship
David M. Holtzman, MD, of WashU Medicine, was recognized by the National Institute of Neurological Disorders and Stroke for impactful mentorship of future scientists.
Mitreva receives award for parasite research
WashU Medicine researcher Makedonka Mitreva was honored with the Ward Medal from the American Society of Parasitologists for her use of genetics and genomics to understand parasitic worms.
Study reveals how ketamine interacts with opioid receptors
WashU Medicine researchers have uncovered new insights into the pharmacology of ketamine that help explain both its rapid benefits and its risks.
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