New Alzheimer’s prevention trial in young people

Researchers at Washington University School of Medicine are conducting an Alzheimer’s prevention trial with young adults from high-risk families to evaluate whether an investigational drug can clear a key Alzheimer’s protein, amyloid beta, and slow or stop the disease.

A pathway emerges

heme transporter
Scientists at Washington University in St. Louis described for the first time the structure of a bifunctional protein, called CcsBA, that transports heme and attaches it to cytochromes. The study led by Robert Kranz, professor of biology in Arts & Sciences, captured two conformational states of CcsBA, a bacterial and chloroplast protein, allowing researchers to characterize the enzyme mechanism.

Marcus receives NIH grant

Daniel Scott Marcus, professor of radiology at the School of Medicine, received a one-year $2 million grant from the National Institutes of Health (NIH).