Second cycle of grants supports patient research

Twenty-four research groups have received funding through a joint Clinical and Translational Research Funding Program offered by the Washington University Institute of Clinical and Translational Sciences (ICTS) and the Barnes-Jewish Hospital Foundation (BJHF). This initiative combines the former ICTS Pilot and Novel Methodologies Program and the BJHF Clinical/Translational Research Grant Program.

In November 2008, 118 proposals were submitted. Proposals were either planning grants (up to $25,000) or research grants (up to $75,000). Twelve were awarded by ICTS and 12 by BJHF for a total of $1.4 million. Awards began June 1.

ICTS was established in 2007 under a $50 million, five-year grant from the National Institutes of Health’s Clinical and Translational Science Award program. Kenneth S. Polonsky, M.D., the Adolphus Busch Professor and head of the Milliken Department of Medicine, directs the institute.

The programs and services of ICTS are designed to bring together basic research scientists and clinical researchers as well as health-care and commercial institutions in a coordinated system dedicated to improving patient care. Collaborating institutions include WUSTL, BJC HealthCare, Saint Louis University, the University of Missouri-St. Louis College of Nursing, Southern Illinois University Edwardsville School of Nursing, St. Louis College of Pharmacy and others.

Visit icts.wustl.edu for more information.


2009 grant recipients

• Research network for studies of children with unilateral hearing loss, Judith Lieu, M.D., assistant professor of otolaryngology

• Causes of fever in children 2-36 months of age, Gregory Storch, M.D., the Ruth L. Siteman Professor of Pediatrics

• Structural immunology of hepatitis C virus and generation of epitope diagnostics, Michael Diamond, M.D., Ph.D., associate professor of medicine (infectious diseases)

• Human and mouse linked evaluation of cancer core facility, Matthew Ellis, M.D., Ph.D., professor of medicine (oncology)

• Clinical research core facility for adminstrative claims data, Victoria Fraser, M.D., the J. William Campbell Professor of Medicine (infectious diseases)

• Community care for croup, Jane Garbutt, M.B.Ch.B., research associate professor of medicine (general medical sciences)

• Dissemination and implementation research core, Enola Proctor, Ph.D., the Frank J. Bruno Professor of Social Work Research

• Neuropathology of chronic manganese exposure, Brad Racette, M.D., professor of neurology

• Characterization of CD34 stem cells and T cells following AMD3100 mobilization, Michael Rettig, Ph.D., research assistant professor of medicine (oncology)

• The role of neurobeachin (NBEA) in multiple myeloma, Michael Tomasson, M.D., associate professor of medicine (oncology)

• Improving kidney transplant education to increase living donation rates, Amy Waterman, Ph.D., assistant professor of medicine (general medical sciences)

• Nutrient-metabolite responses and arrhythmic outcomes in cardiomyopathy patients, Peter Crawford, M.D., Ph.D., assistant professor of medicine (cardiovascular division)

• Environmental moderators of diabetes, self-management education, Michael Elliott, Ph.D., research assistant professor of social work

• Increased SMN as a therapy for ALS, Timothy Miller, M.D., Ph.D., assistant professor of neurology

• Radiologic predictors of functional outcome in newborn brachial plexus injury, Craig Zaidman, M.D., instructor in neurology

• Osteomyelitis in diabetic foot infections: Impact of bone biomarkers, Hilary Babcock, M.D., assistant professor of medicine (infectious diseases)

• Running the stop in bone marrow failure, Monica Bessler, M.D., Ph.D., professor of medicine (hematology)

• Directional diffusivity as a window into the pathology of MS, Anne Cross, M.D., professor of neurology

• Role of occulomotor control in Parkinsonian gait: Mechanisms and treatment, Gammon Earhart, Ph.D., assistant professor of physical therapy

• Developing virtual environment authoring tools for creating therapy interventions, Jack Engsberg, Ph.D., associate professor of occupational therapy

• An interdisciplinary approach to the study of NAFLD, Robert Gropler, M.D., professor of radiology

• Multicontrast MRI for improved tumor localization in prostate cancer, Robert Grubb, M.D., professor of surgery (neurological surgery)

• Molecular epidemiology of S. aureus bacteremia and clinical outcomes, David Warren, M.D., assistant professor of medicine (infectious diseases)

• Patterns of prenatal tobacco use and psychiatric disorders, Louise Flick, Dr.PH., professor of family health and community health nursing at Southern Illinois University Edwardsville School of Nursing