Engineering proteins to help counter devastating diseases

Engineering proteins to help counter devastating diseases

Meredith Jackrel, assistant professor of chemistry in Arts & Sciences, recently received a five-year grant from the National Institutes of Health (NIH) and another from the Longer Life Foundation to study protein disaggregases —  evolved protein forms that mitigate protein misfolding — as a strategy to combat neurodegenerative diseases such as Alzheimer’s, Parkinson’s and ALS.
Blodgett awarded CAREER grant to study biosynthetic silence

Blodgett awarded CAREER grant to study biosynthetic silence

Joshua Blodgett, assistant professor of biology in Arts & Sciences, received a five-year $900,500 grant to support his research related to actinomycete bacteria. This type of bacteria produces a majority of current antibiotics and may harbor other useful small molecules that could be revealed by activating silent genes.
Better together: Mitochondrial fusion supports cell division

Better together: Mitochondrial fusion supports cell division

New research from Gary Patti’s laboratory in Arts & Sciences shows that when cells divide rapidly, their mitochondria are fused together. In this configuration, the cell is able to more efficiently use oxygen for energy. This work illuminates the inner workings of dividing cells and shows how mitochondria combine to help cells to multiply in unexpected ways.
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