Newly approved drug effective against lung cancer caused by genetic mutation
The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial. The study is led by scientists at the School of Medicine and other institutions.
New method predicts chemotherapy effectiveness after one treatment
An interdisciplinary team at Washington University finds that combining certain data after a patient’s first treatment can predict how a breast cancer tumor is responding to chemotherapy.
Delaying lung cancer surgery associated with higher risk of recurrence, death
New research from Washington University School of Medicine has found that postponing lung cancer surgery for more than 12 weeks from the date of diagnosis with a CT scan is associated with a higher risk of recurrence and death.
Brain tumors caused by normal neuron activity in mice predisposed to such tumors
Researchers at Washington University School of Medicine and Stanford University have found that normal exposure to light can drive the formation and growth of optic nerve tumors in mice — and maybe people — with a genetic predisposition. Such tumors can lead to vision loss.
Triple-negative breast cancer more deadly for African American women
A new study from Washington University School of Medicine shows that African American women with triple-negative breast cancer have higher mortality than white American women with this aggressive tumor. The investigators call for more research to understand the factors driving the disparities.
Cancer has ripple effect on distant tissues
A new study with zebrafish shows that a deadly form of skin cancer — melanoma — alters the metabolism of healthy tissues elsewhere in the body. The research led by chemist Gary Patti suggests that these other tissues could potentially be targeted to help treat cancer.
Sugar-sweetened drinks linked to increased risk of colorectal cancer in women under 50
A new study led by the School of Medicine has found a link between consuming sugary drinks and an increased risk of colorectal cancer among women under 50. The findings could help explain the rising rates of colorectal cancer among younger adults.
Personalized cancer vaccines for breast, pancreatic cancers show promise
Researchers at Washington University School of Medicine have shown that personalized cancer vaccines made using DNA can program the immune system to attack malignant tumors, including breast and pancreatic cancers.
Women seeking help for unmet needs often overdue for cervical cancer screenings
Scientists at Washington University found in a study that a new, more involved approach is needed to get women who need help with basic resources to undergo screenings for cervical cancer.
Jha to develop imaging methods with $1.8M NIH grant
Abhinav Jha, assistant professor at the McKelvey School of Engineering, has received a four-year $1.83 million grant from the National Institutes of Health (NIH). He will develop a new framework to evaluate quantitative imaging methods and help doctors make better decisions.
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