$3 million grant funds research on mental health challenges of Alzheimer’s
Ganesh Chand, an assistant professor at WashU Medicine Mallinckrodt Institute of Radiology, will study why some Alzheimer’s patients experience neuropsychiatric symptoms such as apathy and depression.
Alzheimer’s disrupts circadian rhythms of plaque-clearing brain cells
In a study published in Nature Neuroscience, researchers at WashU Medicine showed in mice that Alzheimer’s disease upended the daily activity patterns of hundreds of genes in cells that regulate key functions in the brain.
Klinman recognized as outstanding early-career scientist
Eva Klinman, MD, PhD, an instructor in the Department of Neurology at WashU Medicine, has been named a 2025 STAT Wunderkind by STAT News for her exceptional contributions to understanding the mechanisms of brain aging and neurodegeneration.
Circadian clock protein linked to brain aging, neurodegenerative disease
WashU Medicine researchers led by Erik Musiek, MD, PhD, discovered in mice that inhibition of a protein that controls the daily cycling of metabolism and inflammation decreases neurodegeneration in Alzheimer’s disease.
Dai receives $200,000 grant from Alzheimer’s Association
A scientist at Washington University in St. Louis has received a grant from the Alzheimer’s Association to support his research investigating the electrochemistry of neurotoxic protein assemblies.
Yoo, Sun recognized for developing novel method to study aged neurons
Andrew S. Yoo, the Phil and Sima Needleman Distinguished Professor of Developmental Biology at WashU Medicine, and Zhao Sun, a staff scientist in Yoo’s laboratory, have received the Morby Prize from the Cure Alzheimer’s Fund in recognition of their groundbreaking paper that describes a novel method to study aged neurons.
Blood plasma reveals shared pathways in neurodegenerative diseases
WashU Medicine researchers have identified biomarkers of Alzheimer’s, Parkinson’s and frontotemporal dementia from blood plasma, suggesting new therapeutic avenues.
Grant renewal funds research on longevity in mammals
WashU Medicine researcher Benjamin Garcia will receive $18.5 million from the National Institutes of Health (NIH) to study how long-lived mammals stay healthy into old age.
Sleep aid blocks neurodegeneration in mice
A new study by WashU Medicine researchers suggests that lemborexant and sleep aids that work the same way could help treat or prevent damage caused by harmful buildup of the protein tau in multiple neurodegenerative diseases, including Alzheimer’s.
Drug to slow Alzheimer’s well tolerated outside of clinical trial setting
In a recent study, WashU Medicine researchers found adverse events were rare and manageable among patients with very mild or mild Alzheimer’s disease who received infusions of a next-generation Alzheimer’s medication.
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