School of Medicine

Scientists at the School of Medicine have received a $3.7 million grant from the National Institutes of Health (NIH) to support an open-source database aimed at boosting personalized approaches to cancer treatment.

Premature infants are at high risk of developing life-threatening lung infections, partly because their lungs are underdeveloped at birth. A new study from Washington University School of Medicine in St. Louis has found, in mice, that an inhaled drug promotes the development of lung immunity and reduces the risk of pneumonia.

David Holtzman, MD, the Andrew B. and Gretchen P. Jones Professor at Washington University School of Medicine, has received the August M. Watanabe Prize in Translational Research from the Indiana Clinical and Translational Sciences Institute. He was recognized for his work uncovering the causes of Alzheimer’s disease and translating an understanding of its basic biology into potential therapies.

A School of Medicine study has found that brain immune cells called microglia form the crucial link between protein clumping and brain damage. Suppressing such cells might prevent or delay the onset of dementia in people.

Physician-scientist and rheumatologist John P. Atkinson, MD, the Samuel B. Grant Professor of Medicine at Washington University School of Medicine in St. Louis, has been awarded the Presidential Gold Medal by the American College of Rheumatology.

A new study from Washington University School of Medicine in St. Louis suggests the gut microbiome has an impact on how the body breaks down processed foods, such as cereals, pastas, chocolate and soda. The new knowledge could help in the development of healthier, more nutritious processed foods.

A longtime leader in microbiome research, the School of Medicine plans to expand research into the microbiome with a new mouse facility that will further enable researchers to understand how microbes influence health and disease. The facility will be funded with an $8 million grant from the National Institutes of Health and an additional $2.8 million from the School of Medicine.

David Gutmann, MD, PhD, the Donald O. Schnuck Family Professor of Neurology at the School of Medicine, has received a second Einstein Visiting Fellowship from the Berlin Institute of Health to study how immune cells in the brain known as microglia are linked to cancer, vision loss and behavioral problems in the disease neurofibromatosis type 1.

An immune cell that helps set the daily rhythms of the digestive system has been identified by researchers at the School of Medicine. The findings open the door to new treatments for digestive ailments targeting such cells.

One of the most frequently performed weight-loss surgeries in the world — Roux-en-Y gastric bypass — is effective, but another procedure rarely performed in the U.S. appears to be more effective at eliminating type 2 diabetes in patients with obesity. A study from the School of Medicine explains why.