Pursuing a precision paradigm

Dean David Perlmutter, MD, is aligning resources at the School of Medicine to focus on ­personalized, precision ­medicine: managing health ­instead of disease, providing the right ­treatment for the right patient, and developing drugs and other ­therapies faster and at lower cost.
Why move from current standards of patient care to a more personalized approach to treatment? Experts at the School of Medicine describe today’s medical landscape as they plan for the care — and cures — of the future.

Building the foundation for discovery

The School of Medicine is building the necessary infrastructure through centers and institutes to allow research that is more efficient and cost-effective, and that encourages high risks leading possibly to key breakthroughs.

Undaunted explorer

Timothy Ley, MD, the Lewis T. and Rosalind B. Apple Professor of Medicine, is a hematologist, oncologist and cancer biologist. For decades, the Ley lab has used mouse models of acute myeloid leukemia to establish key principles of AML pathogenesis. (Photo: James Byard)
Timothy Ley, MD, has been investigating leukemia, particularly acute myeloid leukemia (AML), for decades. His research team now knows the mutations they need to go after ­aggressively, the nature of the ­mutations that need to be targeted and why patients relapse.

A promising future

Cheryl Leyns is among the promising graduate students spread out across the School of Medicine. She works in David Holtzman’s lab, researching pathologies of Alzheimer’s disease. (Photo: James Byard)
At Washington University, training the next generation of leaders in translational medicine is a key focus. Here, Cheryl Leyns and Phat Huynh share stories of working in the lab of David Holtzman, MD, researching pathologies of Alzheimer’s disease.

Working with emotions

(Illustration composite: Monica Duwel)
Hillary Anger Elfenbein, an organizational behavior expert, studies emotions in the workplace — how easy they are to miss or misinterpret, and how they impact performance.

The problem with food

The way we’re feeding ourselves is devastating rainforests, widening waistlines, exploiting small landholders and causing thousands of pounds of food to go to waste. Alumni and Washington University researchers are working hard to change how we put food on our table.

Quoted: Hold That Thought

These quotes are from Hold That Thought, a podcast produced by Arts & Sciences, where in 15 minutes you can learn about the allure of Shakespeare, the most attractive personality traits or the secrets stored in rocks.