Genes linked to Alzheimer’s risk, resilience ID’d

A team led by researchers at the School of Medicine in St. Louis has identified a pair of genes that influence risk for Alzheimer’s disease. The genes — known as MS4A4A and TREM2 — affect the brain’s immune cells. They influence Alzheimer’s risk by altering levels of TREM2, a protein that is believed to help microglia cells clear excessive amounts of the Alzheimer’s proteins amyloid and tau from the brain.

WashU Expert: Proposed changes will stamp out ‘countless species’

grizzly bear
The Trump Administration’s proposed overhaul of the landmark Endangered Species Act will “hasten the extinction of countless species,” says Jonathan Losos, director of the Living Earth Collaborative at Washington University in St. Louis and an international biodiversity expert.

Andrea Wang-Gillam

Andrea Wang-Gillam
Andrea Wang-Gillam, MD, PhD, is an oncologist at Siteman Cancer Center whose family’s careers inspired her lifelong interest in helping people through medicine. Today she aims to improve outcomes for patients with pancreatic cancer.

Which city is most polluted? No one knows

smog
Of all the reasons why researchers would prefer more robust monitoring of pollutants in the atmosphere, one stands out: Having this basic information is an indication of progress in the realm of environmental science. A McKelvey School of Engineering scientist outlines the extent of the gap between what researchers know and don’t know.

Gut makeup could make diarrhea less likely

Researchers at the School of Medicine have found the molecular signature of a healthy gut microbial community – the kind that can keep the intestinal bacteria Clostridium difficile (C. difficile) from overgrowing and causing diarrhea.