Unlikely gene variants work together to raise Alzheimer’s risk

Studying spinal fluid from people at risk for Alzheimer’s disease, School of Medicine researchers have found that a gene variation that had not been considered risky actually can increase the chances of developing Alzheimer’s disease when it occurs in tandem with another gene variant known to elevate risk. Shown is an image of a brain with a buildup of amyloid deposits (highest amounts in yellow and red) that collect to form senile plaques in patients with Alzheimer’s.
Ignorance is sometimes bliss

Ignorance is sometimes bliss

Evolutionary biologist W.D. Hamilton predicted that organisms ought to evolve the ability to discriminate degrees of kinship so as to refine their ability to direct help to individuals with whom they shared the most genes. But two WUSTL biologists point out that there seem to be many cases where “a veil of ignorance” prevents organisms from gaining this kind of information, forcing them to consider a situation from the perspective of all members of their group instead of solely from their own perspective or that of their close kin.

Kharasch, Sadler elected to Institute of Medicine

The School of Medicine’s Evan D. Kharasch, MD, PhD (left) and J. Evan Sadler, MD, PhD, have been elected to the Institute of Medicine of the National Academy of Sciences, one of the highest honors medical scientists in the United States can receive.

Butterfly Garden celebrates 17th birthday, honors longtime leaders

The 17th birthday celebration of the Elizabeth Danforth Butterfly Garden, held Oct. 6, drew 60 guests to enjoy the garden and honor longtime volunteer leader Jean Davis. The garden was dedicated in 1996 in honor of Elizabeth Gray Danforth, the late wife of Washington University Chancellor Emeritus William Danforth.

Study suggests private NICU rooms may influence preemies’ development

Premature babies often spend their first months of life in neonatal intensive care units (NICUs) — environments that, in recent years, have seen transformations, with hospitals adding private rooms to NICUs in place of open wards. But research at the School of Medicine adds new information to the discussion over what is the optimal setting for infants in the NICU. Shown is the study’s first author, Bobbi Pineda, PhD, in the NICU at St. Louis Children’s Hospital.

New clue to aggressive brain tumors

Scientists at the School of Medicine have identified a biological marker that may help predict overall survival of people with deadly brain tumors. The marker is made by noncancerous cells known as monocytes (pictured in brown).

Amy Leach to read Oct. 24

At 8 p.m. Thursday, Oct. 24, Leach will read from her work as part of The Writing Program’s fall Reading Series. The talk, which is free and open to the public, will take place in Hurst Lounge, Room 201, Duncker Hall. A reception and book signing will immediately follow.

Basij-Rasikh delivers a simple but powerful message for the Assembly Series: ‘Educate a girl. Change the world’

Growing up under Taliban rule in Afghanistan, Shabana Basij-Rasikh’s family literally risked their lives to provide an education for their daughters. She learned early on the danger females face in seeking an education but she also experienced its rich rewards. Today she is paying her good fortune forward to empower some of the estimated 66 million girls who are denied a primary education. Her message is simple: “Educate a girl. Change the world.” She delivers that message at 4 p.m. Friday, October 25 in Graham Chapel for the Assembly Series/Olin Fellowship Conference Lecture.
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