New insight into role of amyloid beta in Alzheimer’s disease

New insight into role of amyloid beta in Alzheimer’s disease

New Alzheimer’s disease research details a technique that speedily measures levels in the brain of a damaging protein fragment, and insight into why mutations in a specific gene increase the risk of developing the disease. Both studies, from researchers at Washington University School of Medicine in St. Louis, are available online in The Journal of Experimental Medicine.
Probing proteins’ 3-D structures suggests existing drugs may work for many cancers

Probing proteins’ 3-D structures suggests existing drugs may work for many cancers

Examining databases of proteins’ 3-D shapes, scientists at School of Medicine have identified more than 850 DNA mutations that appear to be linked to cancer. The information may expand the number of cancer patients who can benefit from existing drugs. The study, published June 13 in Nature Genetics, detailed a list of the mutations and associated drugs that may work against them.
30 years of public art

30 years of public art

It began as an experiment. Three decades later, the University City Public Art Series is the nation’s longest-running public art collaboration between a university and a local municipality.
Celebrate or commemorate?

Celebrate or commemorate?

Recent research has indicated a general consumer preference for experiences over material goods when it comes to giving and receiving gifts. But new findings from researchers at Olin Business School at Washington University in St. Louis show that major life events might be the exception to that rule.
Wandering ice on Mars

Wandering ice on Mars

Glaciations on Mars are different from those on Earth. During a Martian glacial period, water vapor that would otherwise travel to the north polar cap instead snows out at lower latitudes, where ice then accumulates. Radargrams of the north polar region of Mars record the most recent mid-latitude Martian glacial period and the regrowth of the polar ice since then.
Five-cent chemistry

Five-cent chemistry

The research team of Liviu Mirica, associate professor of chemistry in Arts & Sciences, has developed novel methods for generating the buildings blocks of important compounds with the common metal nickel. The work expands scientists’ toolbox for nickel-based chemistry, and contributes to the movement of “green chemistry” toward a 21st century of sustainable synthesis.
Pluto: A cosmic lava lamp

Pluto: A cosmic lava lamp

Using computer models, New Horizons team members have been able to determine the depth of the layer of solid nitrogen ice within Pluto’s distinctive “heart” feature — a large plain informally known as Sputnik Planum — and how fast that ice is flowing. “For the first time, we can really determine what these strange welts of the icy surface of Pluto really are,” said William B. McKinnon, who led the study.
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