A ring to bind them

A ring to bind them

Using genomics, a chemistry lab has worked out the biosynthetic machinery that makes a new class of antibiotic compounds called the beta-lactones. Like the beta-lactams, such as penicillin, they have an unstable four-member ring. The key to their antibiotic activity, it is also difficult to synthesize.
Death by volcano?

Death by volcano?

The discovery of anomalously high levels of mercury in rocks from the Ordivician geological period has led to a new interpretation of the ensuing mass extinction. A sequence of disturbances may have led to catastrophic cooling by reflective sulfate aerosols injected into the atmosphere by massive volcanism. The finding is important since aerosol cooling is under consideration as a way to temper global warming.
New use for a pesky weed

New use for a pesky weed

Dandelions are much-maligned weeds, with a paratrooper-like seed dispersal system that makes them difficult to eradicate. However, new research from an engineer at Washington University in St. Louis finds a great benefit in an unlikely place for the pesky dandelion: each of its tiny seeds can be used as a perfect pipette in the laboratory setting.
A simple sniff

A simple sniff

A team of engineers from Washington University in St. Louis has combined nanoparticles, aerosol science and locusts in new proof-of-concept research that could someday vastly improve drug delivery to the brain, making it as simple as a sniff.
Studying the brain’s suspension system in TBIs

Studying the brain’s suspension system in TBIs

Traumatic brain injury, or TBI, can be devastating and debilitating. Researchers know that the membranes separating the skull from the brain play a key role in absorbing shock and preventing damage caused during a head impact, but the details remain largely mysterious. New research from a team of engineers at Washington University in St. Louis takes a closer at this “suspension system” and the insight it could provide to prevent TBI.
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