Medicine & Health

Tiny tropical fish are helping scientists understand human development and disease, from birth defects and cancer to muscle and nerve disorders. Contributing to this effort, Washington University is now home to one of the largest zebrafish facilities in the world. And with robotic feeding and cleaning systems, it is the world’s most modern.

Two new studies showcase the dynamic relationship between components of the diet and the intestinal microbiome. The research provides a foundation for improving human health by designing diets and foods that enhance microbes’ ability to capture specific food ingredients or that enrich the presence of beneficial microbes.

The Friedman Conference on Aging will be held from 8:30-11 a.m. Tuesday, May 24, 2011, in the Connor Auditorium in the Farrell Learning and Teaching Center. It is sponsored by the Harvey A. Friedman Center for Aging. No registration is required.

For years, the field of optical imaging in biological tissue had languished, with few advances and no significant growth. The concept was promising — using light to image organs, cells, and blood vessels, noninvasively and without any radiation — but it seemed impossible to obtain high-resolution images at any significant depth. Then came Lihong V. […]

What does it take to regenerate a limb? Biologists have long thought that organ regeneration in animals like zebrafish and salamanders involved stem cells that can generate any tissue in the body. But new research from Washington University School of Medicine in St. Louis has shown that the individual cells in a regenerating limb retain their original identities and only give rise to more of their own kind.

Researchers at Washington University and King’s College London have independently identified DNA on chromosome 3 that appears to be related to depression. The new studies identify a DNA region containing up to 90 genes. Both are published May 16 in the American Journal of Psychiatry. 

Phillip Tarr, MD, is a busy investigator juggling meetings, research, teaching and patient care. And he is a man driven to find answers to fight deadly diseases in newborns.

David E. Kennell, PhD, professor emeritus of molecular microbiology, died April 20, 2011. He was 78 and lived in University City, Mo.

Washington University has awarded five Bear Cub Fund grants totaling $240,000 to support innovative research that has shown commercial potential.

New data offer hints to why Parkinson’s disease so selectively harms brain cells that produce the chemical dopamine, says Karen O’Malley, PhD, a researcher at Washington University School of Medicine in St. Louis.