Simple blood test predicts neurotoxic complications of CAR-T cell therapy
A new study from Washington University School of Medicine suggests a simple blood test — administered before CAR-T cell treatment is initiated — may identify which patients are predisposed to developing neurotoxic side effects after CAR-T cell therapy, which is used to treat several cancers.
Drug combo therapy in mice blocks drug resistance, halts tumor growth
An experimental combination of two drugs halts the progression of small cell lung cancer, the deadliest form of lung cancer, according to a study in mice from researchers at Washington University School of Medicine in St. Louis and colleagues.
Study offers insights into how pancreatic cancer develops
A new study from Washington University School of Medicine has revealed the details of two key transition points in the development of pancreatic cancer. The study provides insights into treatment resistance and how immunotherapy could be harnessed to treat this aggressive tumor type.
Sugar metabolism is surprisingly conventional in cancer
A study in Molecular Cell led by chemist Gary Patti in Arts & Sciences shows that cancer cells don’t want to waste glucose, they just consume it too quickly. The discovery was made possible with metabolomics, which allowed Patti and his team to observe the speed at which small molecules move through cells.
New imaging-based approach to measure radiation dose
Abhinav Jha and his collaborators have developed a way to measure the distribution of dangerous radiation associated with cancer treatments.
Health insurance impacts cancer stage at diagnosis in minority children
Disparities in cancer stage at diagnosis among racial and ethnic minority children and adolescents may be partially explained by health insurance coverage, finds a study from the Brown School at Washington University in St. Louis.
Pairing imaging, AI may improve colon cancer screening, diagnosis
A new technological pairing from the lab of Quing Zhu at the McKelvey School of Engineering may lead to an improved diagnostic tool for colorectal cancer.
$5.3 million grant supports research into lung cancer recurrence
A National Institutes of Health (NIH) grant to Washington University School of Medicine will support research into understanding lung cancer recurrence.
Immunity-boosting treatment enhances CAR-T cell therapy for blood cancers
A study from the Washington University School of Medicine shows that treatment with the immunity boosting protein interleukin 7 (IL-7) after an infusion of genetically modified T cells causes the cancer-fighting CAR-T cells to grow in number and become more effective at killing tumor cells.
Researchers to study leader cells in breast cancer model
Gregory D. Longmore, MD, at the School of Medicine, and Amit Pathak, at the McKelvey School of Engineering, will study the cells that lead the migration of deadly tumor cells through the body with a five-year $2.54 million National Institutes of Health (NIH) grant.
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