Jennifer E. Layden


Associate Dean for Practice, Professor, Bursky Public Health

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Jennifer Layden, MD, PhD, has worked across the public health system — as an infectious diseases physician and epidemiologist and in leadership roles in city, state and federal public health. She brings an on-the-ground understanding of how health threats are detected, how officials assess risk, how scientific evidence becomes public health guidance and how agencies respond.

Layden is associate dean for practice and a professor at the Bursky School of Public Health.

Before joining WashU, she served as a senior vice president at the Association of State and Territorial Health Officials, working to strengthen health department capacity, data modernization, workforce and infrastructure. Previously, she was a senior executive and inaugural director of the Centers for Disease Control and Prevention’s Office of Public Health Data, Surveillance and Technology, where she led the agency’s Data Modernization Initiative and expansion of near-real-time public health reporting and analytic capacity.

Earlier, Layden was deputy commissioner and chief medical officer for the Chicago Department of Public Health and incident manager for the city’s COVID-19 response. She also served as state epidemiologist and chief medical officer for the Illinois Department of Public Health. Her academic research has included infectious disease epidemiology, including viral hepatitis transmission, treatment response and disease progression.

Areas of expertise

  • Infectious diseases and emerging outbreaks — transmission, risk, prevention and public health response
  • Vaccines and immunization — vaccine guidance, vaccine-preventable diseases, immunization programs and changing or conflicting recommendations
  • Foodborne illness and recalls — outbreak detection and investigation, consumer risk and prevention
  • Disease surveillance and outbreak detection — how health officials identify and track emerging threats
  • Public health preparedness and emergency response — how local, state and federal agencies prepare for and manage health emergencies
  • Public health data and modernization — disease reporting, surveillance, informatics and faster public health decision-making
  • AI in public health practice — opportunities for AI in surveillance, outbreak detection, communications and operations; governance, privacy, bias and human oversight
  • Governmental public health — CDC and state and local health department operations, workforce, infrastructure and translating evidence into action

Recent work

The Artificial Intelligence Divide: A Call to Action for State and Territorial Public Health — American Journal of Public Health, October 2026

Reimagining Governmental State and Local Public Health Practice in the Era of Artificial Intelligence: Why Public Health Must Engage With AI Now — American Journal of Public Health, September 2026

A Unified Approach to Health Data Exchange: A Report From the US DHHS — JAMA, March 2025

Infectious disease surveillance needs for the United States: lessons from Covid-19 — Front Public Health, July 2024

In the media

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