School of Medicine researchers are seeking women who’ve had two or more unexplained first-trimester miscarriages to evaluate an experimental treatment to help women carry babies to term.
“Recurrent pregnancy loss affects 2 percent to 5 percent of couples trying to conceive, and specific causes are only identified in 50 percent of these patients,” said Kelle H. Moley, M.D., associate professor of obstetrics and gynecology and primary investigator of the study.
“Past uncontrolled studies have suggested that Metformin can prevent recurrent miscarriages. Our study will determine if it does and provide some new insight on the mechanism responsible.”
Women between 21-34 are eligible for the six-month study. Participants will be randomly assigned to either receive the drug Metformin or an inactive pill twice a day.
Once a participant becomes pregnant, she will receive early prenatal care, including weekly blood work and ultrasounds free of charge.
Ten percent to 15 percent of women who take Metformin experience side effects such as nausea and diarrhea.
For more information or to participate in the study, call 286-2419.