Washington University

Researchers, including Richard Wilson, PhD, director of The Genome Institute, have identified the first gene mutation associated with a chronic and often fatal form of neuroblastoma that typically strikes adolescents and young adults. The finding provides the first clue about the genetic basis of the long-recognized but poorly understood link between treatment outcome and age at diagnosis.

Robert S. Brookings played a pivotal role in the development of what is now WUSTL’s Danforth Campus. He also founded the Brookings Institution, which now enjoys an academic partnership with WUSTL. He will be honored June 22 and 23 with a lecture and a star on St. Louis’ Walk of Fame.

Washington University has the only Emergency Medical Services (EMS) program in Missouri that routinely sends emergency medicine physicians along with its own ambulances to treat trauma patients at disaster scenes.

Girls and young women who drink alcohol increase their risk of benign (noncancerous) breast disease, says a study by researchers at Washington University School of Medicine in St. Louis and Harvard University. Benign breast disease increases the risk for developing breast cancer. 

A five-year, $3.7 million clinical trial will investigate how to balance the benefits and risks of warfarin, a drug that helps prevent potentially deadly blood clots. The multicenter study, led by researchers at Washington University School of Medicine in St. Louis, will evaluate customized warfarin dosage based on patient genetics and will test which range of blood clotting is optimal in orthopedic patients.

Dolphins, whales and porpoises have extraordinarily small balance organs, and scientists have long wondered why. In a head to head comparison of two dolphins and a rodeo bull, Washington University School of Medicine researchers have contradicted the leading explanation for these undersized organs and left the door open for new theories.

Researchers at Washington University School of Medicine in St. Louis have shown once again that “ready, fire, aim,” nonsensical though it may sound, can be an essential approach to research.

The first head-to-head comparison of therapeutic monoclonal antibodies produced from plants versus the same antibodies produced from mammalian cells has shown that plant-produced antibodies can fight infection equally well. Scientists conducted the comparison as a test of the potential for treating disease in developing nations with the significantly less expensive plant-based production technique.

Scientists at Washington University School of Medicine in St. Louis have identified a protein made by the malaria parasite that is essential to its ability to take over human red blood cells. “Without this protein … the infectious process stops,” says Dan Goldberg, M.D.

Cleft palate has been linked to dozens of genes. During their investigation of one of these genes, researchers at Washington University School of Medicine in St. Louis were surprised to find that cleft palate occurs both when the gene is more active and when it is less active than normal.