Immune cell implicated in development of lung disease following viral infection
Scientists at the School of Medicine have implicated a type of immune cell in the development of chronic lung disease that sometimes is triggered following a respiratory viral infection. The study was published in The Journal of Immunology.
School of Medicine researchers develop COVID-19 nasal vaccine
Scientists at Washington University School of Medicine in St. Louis have developed a vaccine that targets the SARS-CoV-2 virus, can be given in one dose via the nose, and is effective in preventing infection in mice susceptible to the novel coronavirus. The investigators—Michael S. Diamond, MD, PhD the Herbert S. Gasser Professor of Medicine and […]
Clinical trial in children to investigate rare inflammatory disorder linked to COVID-19
Washington University pediatricians who treat patients at St. Louis Children’s Hospital are part of a major research effort to investigate how the novel coronavirus affects children and young adults, including its role in a rare but serious inflammatory syndrome.
Bowman receives grant to study Alzheimer’s disease
Gregory Bowman, associate professor of biochemistry and molecular biophysics at the School of Medicine, received a three-year $1,763,634 grant award from the National Institute on Aging of the National Institutes of Health (NIH) for his research titled “Structural basis for ApoE4-induced Alzheimer’s disease.”
Walking pace among cancer survivors may be important for survival
A new study from Washington University School of Medicine in St. Louis and the National Cancer Institute finds a possible link between slow walking pace and an increased risk of death among cancer survivors.
New evidence COVID-19 antibodies, vaccines less effective against variants
School of Medicine researchers have found that new variants of the virus that causes COVID-19 can evade antibodies that work against the original form of the virus, potentially undermining the effectiveness of vaccines and antibody-based drugs being used to prevent or treat COVID-19.
Opioid overdose reduced in patients taking buprenorphine
The drug buprenorphine is an effective treatment for opioid use disorder, but many who misuse opioids also take benzodiazepines to treat anxiety and similar conditions. School of Medicine researchers found that buprenorphine lowered the overdose risk, even in people who also took benzodiazepines such as Valium or Xanax.
COVID-19 can kill heart muscle cells, interfere with contraction
A study from Washington University School of Medicine in St. Louis provides evidence that the coronavirus that causes COVID-19 can invade and replicate inside heart muscle cells, causing cell death and interfering with heart muscle contraction.
Electrical signaling in cells focus of $8.8 million grant
Researchers at Washington University School of Medicine have received an eight-year, $8.8 million grant to study ion channels as potential targets for new drugs to treat disorders affecting the brain, heart and muscles.
Holtzman, Karch honored for research into neurodegenerative diseases
Alzheimer’s researchers David M. Holtzman, MD, and Celeste Karch, PhD, at the School of Medicine, have been recognized by the Rainwater Charitable Foundation for scientific achievements that could lead to new, effective treatments for neurodegenerative diseases associated with the accumulation of tau protein in the brain. Alzheimer’s is the best known such disease.
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