Enhancing the lives of children

The late 1960s were a time of change and personal reflection. Neil H. White was a student at the State University of New York at Albany, pondering his own future and considering three professions: chemical engineer, ski bum or doctor. Although he was a chemistry and physics major, White also was president of the Ski […]

Make me a match

Photo by Bob BostonOn Match Day March 17, medical students across the United States learned which residency programs they will enter.

World’s top scholars on modern human origins to gather at Washington University

Some of the world’s top scholars on modern human origins will gather March 26 at Washington University in St. Louis for the last of a four-part series of “Conversations” on key issues that will affect the future of the university, the community and the world. Arts & Sciences is sponsoring the “Conversations,” which are free and open to the public, as part of the university’s 150th anniversary celebration. The “Modern Human Origins” Conversation will be held from 10 to 11:30 a.m. in Graham Chapel.

Gene may increase risk for type 2 diabetes

Two international research teams — one led by M. Alan Permutt, M.D., professor of medicine and of cell biology and physiology at Washington University School of Medicine in St. Louis — have found variations in a gene that may predispose people to type 2 diabetes, the most common form of the disease. The two research teams, which collaborated extensively, will report their findings in companion articles in the April issue of Diabetes.

Diabetes progress

The results of an experimental cross-species transplant suggest the innovative approach might halt type 1 diabetes while greatly reducing the risk of rejection. Click here for more medical articles

Alzheimer’s clues in skin cells

A fluroescent-tagged antibody bearing silver and gold particles reveals I and L bradykinin receptors lit in a ghostly green glow on the surfact of cultured human cellsPreliminary research suggests it may someday be possible to diagnose and forecast risk for Alzheimer’s disease using skin cells, thanks to a small protein, or peptide, that few previously associated with the disease. Researchers at Washington University School of Medicine in St. Louis have discovered that skin cells from people with inherited forms of Alzheimer’s disease respond to the peptide by triggering Alzheimer’s-like changes, but skin cells from healthy individuals do not. They say the findings need to be explored further in cases of non-inherited Alzheimer’s disease, but the results could eventually lead to a way of determining an individual’s risk of developing Alzheimer’s before clinical symptoms arise.

Unused kidneys

Kidney recipient Barry Hammond (left) and his brother, kidney donor Brian.More than 50,000 people in the United States are waiting for kidney transplants. Most are waiting for someone who wants to be an organ donor to die, but each year only 9,000 people on the transplant waiting list get a kidney from someone who has died, while 16,500 on the list die. Transplants from living donors have the greatest chance of working for a long time and can happen quickly, often within a year. A living kidney donor may be a family member or friend between the ages of 18 and 65. They must be healthy and have a blood type that is compatible with the recipient’s blood type. But researchers at Washington University School of Medicine, have discovered something surprising. Many interested kidney donors are not taken up on their offers to donate because the recipients are afraid donors will be harmed. As a result, many potential donor kidneys go unused.
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