Unveiling insulin insights

Good science requires knowing when to drop bad ideas, explains Michael M. Mueckler, Ph.D., professor of cell biology and physiology. “You may have worked on something for two or three years,” he says. “But at some point, you have to look at the long series of results, use the data to evaluate your original hypothesis […]

Petersen named McDonnell professor

Steven E. Petersen is congratulated by Chancellor Mark Wrighton and William A. Peck.Steven E. Petersen, a pioneering brain imaging researcher, is the first James S. McDonnell Professor in Cognitive Neuroscience.

Preventing kids’ injuries from heavy backpacks

Carrying backpacks the right wayAs parents and kids make their lists for the August back-to-school sales, one item to consider should be a backpack — on wheels, says Nancy J. Bloom, Ph.D., a physical therapy instructor at Washington University School of Medicine in St. Louis. Kids backs are primarily bearing the weight of their schoolbooks. Bloom says that because young bones are growing all the way through high school, heavy backpacks need to be a major concern. She notes that there are a few important things that kids can do to avoid injury, including carrying their backpacks over both shoulders to balance the load.

Finding SARS sooner

Cells afflicted with SARS.Rapid and accurate diagnosis is critical for providing optimum care for patients with SARS and for helping contain the disease and protecting the community. If someone with a severe respiratory illness comes to Barnes-Jewish Hospital or St. Louis Children’s Hospital, emergency department physicians now should be able to tell whether the disease is SARS within a few hours. A team of researchers, led by Michael J. Holtzman, M.D., the Selma and Herman Seldin Professor of Medicine and professor of cell biology and physiology at Washington University School of Medicine in St. Louis, developed a diagnostic tool that allows for quick identification of whether a person with respiratory disease has SARS. They also can determine the severity of the infection, and the test can detect the SARS virus even if very few virus molecules make it into the test sample.

Is there a hospitalist in the house?

ThoelkeIn today’s era of managed care, most physicians have fewer inpatients, and that makes it hard for many to justify spending time at the hospital with those patients. Mark S. Thoelke, M.D., clinical director of the hospitalist service at Barnes-Jewish Hospital and assistant professor of medicine at Washington University School of Medicine in St. Louis, says because hospitalist physicians do not maintain outpatient practices, they can spend all of their time in the hospital and are available to treat a wide range of patients. That also allows for improvements in outpatient care because with their inpatients cared for by hospitalists, primary care physicians can focus even more of their time on the needs of the outpatients who make up the vast majority of their practices.

Pin prick

Sometimes two shots are better than one. Washington University pediatrician, Robert M. Kennedy, M.D., professor of pediatrics, and other Emergency Department researchers at St. Louis Children’s Hospital, have developed an “ouchless” IV technique. Before inserting a big IV needle into the hand of a child, the physicians first apply numbing gel. Then, they use a tiny needle to inject a local anesthetic into the area before they finally introduce the bigger IV needle. By the time an IV is started, the injection site is numb, and patients who already are in an emergency department, don’t have to face even more pain.
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