Bacterial target may be ideal for new drug treatments

E. Coli (yellow) attaches to a host cell using sticky fibersNew insights into the bacteria responsible for urinary tract infections appear to open up an opportunity for disabling a wide range of infectious bacteria. Researchers at the School of Medicine recently revealed how a protein known as PapD helps E. coli assemble sticky fibers called pili that allow the bacterium to latch onto and infect host cells. Scientists are using what they’ve learned to begin designing pilicides, new treatments that stop pili formation and disrupt the infection process.

Incredibly dedicated

Photo by Robert BostonRuth Guzman receives the 2004 Dean’s Distinguished Service Award — the highest honor given to a medical staff member.

Medical malpractice crisis requires major effort from many groups

On the heels of President Bush’s call for medical liability reform during a recent visit to Collinsville, Ill., Washington University hosted a conference on the same topic, “Medical Malpractice and Tort Reform: Finding Truth and Common Ground.” Medical and legal experts gathered to discuss the hard road that must be paved toward a solution for this growing national concern. The consensus of the conference seemed to be that cooperation is the key.
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