Human subjects play mind games

That’s using your brain. For the first time in humans, a team headed by researchers at Washington University in St. Louis has placed an electronic grid atop patients’ brains to gather motor signals that enable patients to play a computer game using only the signals from their brains.

No consensus on when, how, by whom — even if — Alzheimer’s patients are told of their disease

Photo courtesy of Alzheimer’s Association, St. Louis ChapterA WUSTL psychologist says there is little consensus among doctors when it comes to disclosing a dementia diagnosis to patients and their caregivers.To tell or not to tell, that is the question. Should Alzheimer’s disease patients be told of the diagnosis? If so, when, how and by whom? Brian D. Carpenter, Ph.D., an assistant professor of psychology in Arts & Sciences at Washington University in St. Louis, conducted a review of related study literature that shows there is little consensus among clinicians on the issue of disclosing a dementia diagnosis and great room for much more research. Carpenter’s review, done with research assistant Jennifer Dave, was published in the April 2004 issue of The Gerontologist. “If contemporary debate and practice are any indication, there is no consensus on these matters,” Carpenter says in the article “Disclosing a Dementia Diagnosis: A Review of Opinion and Practice, and a Proposed Research Agenda.”

Holidays and special events have no proven effect on the timing of death

WUSTL researchers have found no convincing evidence that people can delay or hasten their own deaths through sheer will.Many of us know stories about terminally ill friends or relatives who were able to battle their illnesses in order to survive until a birthday or other important occasion. In much of medicine, it’s an accepted “truth” that people can hang on or give up and somehow influence the timing of their own deaths. But in reviewing every study on the subject of delaying death, Washington University behavioral medicine researchers have found that there’s no evidence to support the idea that terminally ill people can have an effect on when they die.

Natural mechanism in brain cells may resist stroke damage

In this micrograph of a neuron, green dye highlights proteins linked to nerve cell damage and death during stroke.Brain cells in danger of exciting other nearby brain cells to death may be able to close temporarily, according to new research from Washington University School of Medicine in St. Louis. Scientists simulated stroke-like conditions in cultured rat brain cells that use glutamate, an excitatory chemical messenger linked to nerve damage and death during strokes. But when they created those conditions, the researchers found that glutamate transmission was suppressed in what may be an attempt by neurons to limit the damage caused by catastrophic events such as strokes.

PET scans after therapy improve cervical cancer survival predictions

GrigsbyDoctors regularly use positron emission tomography (PET) scans to diagnose cervical cancer, taking advantage of the technique’s ability to highlight metabolic differences in cancerous tissues. But PET is rarely used for follow-up assessment of cervical cancer patients after treatment. A study in the June 1 issue of Journal of Clinical Oncology shows that post-treatment PET scans could help physicians better predict which patients are largely cancer-free as a result of their treatment and which patients may soon be likely to need additional treatment.
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