Bacterial target may be ideal for new drug treatments

E. Coli (yellow) attaches to a host cell using sticky fibersNew insights into the bacteria responsible for urinary tract infections appear to open up an opportunity for disabling a wide range of infectious bacteria. Researchers at the School of Medicine recently revealed how a protein known as PapD helps E. coli assemble sticky fibers called pili that allow the bacterium to latch onto and infect host cells. Scientists are using what they’ve learned to begin designing pilicides, new treatments that stop pili formation and disrupt the infection process.

New SARS protein linked to important cell doorway

Diagram and image from an experiment that proved SARS makes a protein in infected cellsAs public health officials in China brace for a potential resurgence in SARS (Sudden Acute Respiratory Syndrome) in connection with Chinese New Year on February 9, researchers at Washington University in St. Louis have published insights into a new protein that could be an important contributor to the SARS virus’ ability to cause disease and death.

Incredibly dedicated

Photo by Robert BostonRuth Guzman receives the 2004 Dean’s Distinguished Service Award — the highest honor given to a medical staff member.
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