Disabling gene defuses rheumatoid arthritis in mice

Scientists studying mice have identified a gene that allows immune cells known as neutrophils to protect themselves from the inflammatory chemicals they secrete. Researchers at the School of Medicine showed that knocking the gene out in mice prevented the development of an arthritis-like disorder by making the neutrophils victims of their own damaging secretions.

Community outreach

Courtesy PhotoUniversity physical therapy students worked with St. Louis seniors to help them prepare for the Mature Mile.

A jack-of-all-trades

In its Clinical and Translational Research Program, the Siteman Cancer Center runs about 350 clinical trials simultaneously, gathering health information from hundreds of patients. To set up each study and analyze the resulting data requires expertise in biostatistics. This keeps J. Philip Miller, the biostatistics core director at Siteman, very busy. He and his staff […]

Adult and child brains perform tasks differently

As our brains mature, we tend to use the red regions more frequently for these certain tasks, using the regions represented in blue less.Children activate different and more regions of their brains than adults when they perform word tasks, according to investigators at Washington University School of Medicine in St. Louis. Reporting in the journal Cerebral Cortex, the researchers say those changes in regional brain activity from childhood to adulthood may reflect the more efficient use of our brains as we mature.
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