School of Medicine

In just six months of collaboration, a Department of Energy grand challenge led by Washington University in St. Louis has resulted in the sequencing and annotation of a cyanobacterium that could yield clues to how environmental conditions influence key carbon fixation processes at the gene-mRNA-protein levels in an organism.

Chromosomal damage results in fusion (bottom).Inactivating a protein called mammalian Rad9 could make cancer cells easier to kill with ionizing radiation, according to research at the School of Medicine. The researchers found that Rad9, previously considered a “watchman” that checks for DNA damage, is actually a “repairman” that fixes dangerous breaks in the DNA double helix.

More than 30 Washington University faculty, administrators and staff will participate in science and technology presentations when the American Association for the Advancement of Science (AAAS), the world’s largest general scientific organization, holds its annual meeting Feb. 16-20 at both the America’s Center and Renaissance Grand Hotel in downtown St. Louis.

The compound, called bexarotene, doesn’t cause the severe skin irritations that have limited the use of other vitamin A derivatives in cancer therapies.

Contrary to psychologists’ expectations, breast cancer survivors don’t experience an extended emotional crisis after their treatment regimens end.

Researchers are studying a new drug therapy and are recruiting volunteers for two clinical trials to test the benefits of exercise & the investigational drug.

Photo by Robert BostonPhysical therapy students in “Kinesiology II” try to guess how old Brodie Pratt is by his movements while he plays with his grandmother.

Children between the ages of 6 and 17 years old with moderate-to-severe asthma may be eligible for a study at the School of Medicine to evaluate whether two medications can reduce the amount of inhaled steroids needed to control asthma.

The high-fat “diet” that diabetic heart muscle consumes helps make cardiovascular disease the most common killer of diabetic patients, according to a study done at the School of Medicine. The study will appear in the February 7 issue of the Journal of the American College of Cardiology and is now available online.

Photo by Robert BostonHelping kick off St. Louis Children’s Hospital’s “Building for Care, Searching for Cures” campaign were Joe Buck, Jonathan D. Gitlin, Lee Fetter and Larry Shapiro.The collaboration will focus on accelerating cures in four areas: congenital heart disease, cancer, lung and respiratory disorders and musculoskeletal diseases. More medical news