School of Medicine

Illustration of a lung volume reduction surgeryIn many cases of advanced emphysema, reducing the size of the lungs surgically has been shown to improve both survival and quality of life. But some emphysema patients can’t tolerate this bilateral operation. Now a study conducted by researchers at Washington University School of Medicine in St. Louis and the University of Pennsylvania Health System has shown that unilateral, or one-sided, lung volume reduction surgery has significant benefits, offering help to those who are not candidates for the bilateral surgery. More…

Restricting calories may mean living longer.Can eating a low-calorie yet nutritionally balanced diet extend human life as it does in rodents? Preliminary research suggests it might, so researchers at Washington University School of Medicine in St. Louis are launching a long-term study to find out. More…

Islets isolated from a rat pancreasDiabetes researchers hoping to enlist the help of a protein targeted by cancer therapies have gained an important new insight into how the protein, known as mTOR, works in the pancreas. Ironically, diabetes researchers are hoping to promote the capability of mTOR that oncologists want to shut down: its ability to cause cells to reproduce by dividing into copies of themselves. That capacity can be deadly in tumors, but diabetes researchers want to use mTOR’s ability to make cells divide to maintain enough insulin-making beta cells in the pancreas to prevent diabetes. More…

<img src="/news/PublishingImages/4048_t.jpg" alt="Pretty fly — for a fruit fly. The areas stained blue are regions in the fruit fly where the spineless gene is expressed.” height=”211″ width=”150″ />Pretty fly – for a fruit fly. The areas stained blue are regions in the fruit fly where the spineless gene is expressed.A team of researchers that includes biologists from Washington University in St. Louis has discovered that a gene involved in the development and function of the fruit fly antenna also gives the organism its color vision. Claude Desplan, Ph.D., professor of biology at New York University, and his students made the discovery and provided the data. Ian Duncan, Washington University professor of biology, and his wife, research assistant Dianne Duncan, provided the Desplan laboratory fruit fly (Drosophila) clones and mutants and technical assistance that helped locate where the gene, called spineless, is expressed in the retina. More…

“Da police are not here to create disorder; dere here to preserve disorder.” — Richard J. Daley, Chicago mayor, explaining to the media the role of the police during the riotous 1968 Democratic National Convention. David Kilper/WUSTL PhotoThe order team.Police keep order. That’s why, for example, they issue tickets for “disturbing the peace.” Thus the only logical conclusion to Mayor Daley’s famous quote above — other than dismissing it as the result of a tangled tongue — is sometimes disorder spawns order. Sounds impossible, right? Wrong. According to a computational study conducted by a group of physicists at Washington University in St. Louis, one may create order by introducing disorder. More…

A team of researchers at the School of Medicine is studying how fatty liver disease affects sugar and fat metabolism in overweight adolescents and how losing weight affects the condition. In the last 30 years, the number of overweight children has doubled in the United States, and overweight children are at increased risk for the problem.

Below is a link to the Washington University news release about the U.S. News & World Report undergraduate rankings for 2004-05: http://news-info.wustl.edu/news/page/normal/3627.html To view a full listing of U.S. News magazine, book and Web-only rankings for 2004-05, please visit the U.S. News & World Report site: http://www.usnews.com/usnews/edu/college/rankings/rankindex_brief.php

Three labs independently found no evidence that cells injected from the spleens of healthy mice had formed new insulin-producing beta cells in the diabetic mice. More medical news

After five years of annual mass treatments with two drugs, researchers found that rates of filarial infection, which can lead to disfiguring and disabling elephantiasis, sharply declined in Egypt.

Researchers will study whether combining two blood-pressure drugs will work better than one in slowing the progression of the autosomal dominant polycystic kidney disease.