Drug can quickly mobilize an army of cells to repair injury
Red areas of the circled leg in the right image show increased blood flow due to angiogenic cells.To speed healing at sites of injury – such as heart muscle after a heart attack or brain tissue after a stroke – doctors would like to be able to hasten the formation of new blood vessels. One promising approach is to “mobilize” patients’ blood vessel-forming cells, called angiogenic cells, so these cells can reach the injured area. Recently, researchers at Washington University School of Medicine in St. Louis demonstrated that a drug called AMD3100 can mobilize angiogenic cells from bone marrow of human patients in a matter of hours.
Unusual three-drug combo inhibits growth of aggressive tumors
An experimental anti-cancer regimen combined a diuretic, a Parkinson’s disease medication and a drug ordinarily used to reverse the effect of sedatives. In research conducted at Washington University School of Medicine in St. Louis, the unusual mixture inhibited the growth of aggressive prostate tumors in laboratory mice.
New drug helps treat muscle disease
A new drug has increased survival rates among children with a deadly form of muscular dystrophy called Pompe disease. Now WUSM researchers are testing the drug, Myozyme, in adults with Pompe.
New company uses fruit flies to screen diabetes, cancer drugs
Researchers are confident that their fruit fly model parallels human physiology to a great extent.
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Reversing malnutrition a spoonful at a time
Courtesy PhotoPatricia Wolff, M.D., gives a checkup to a girl in Meds & Food for Kids’ clinic in Haiti.Patricia B. Wolff, M.D., founded Meds & Food for Kids, which works to combat childhood malnutrition in Haiti with a nutrient-rich peanut-butter mixture.
Child Health Research Center gets funding for five additional years
The School of Medicine received a $2 million grant to fund the Child Health Research Center for the next five years.
Unanue named Paul and Ellen Lacy Chair of Pathology
Emil R. Unanue, M.D., internationally recognized as a leader in understanding the immune system, has been named the Paul and Ellen Lacy Professor of Pathology.
El Hombre vs. The Babe
Albert Pujols took part in laboratory tests similar to those conducted on Ruth in 1921.
Previously approved drugs may be helpful in fatal pediatric disorder
A progressive neurodegenerative disorder that is often fatal within the first two decades of life may be treatable via a molecule already targeted by approved drugs, scientists at the School of Medicine and other institutions report.
Washington University physicians adopt electronic medical records
Playing the “where’s-the-chart?” game in the Division of Cardiothoracic Surgery recently became obsolete when the division switched from using paper files to a fully electronic medical record system. The electronic record-keeping system adopted by the cardiothoracic division will be implemented throughout the Washington University Physicians group, a clinical practice group of more than 900 physicians that provides services throughout the region.
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