Future geneticist?

Photo by Tim ParkerSeqwinya Stevens from Beaumont High School in St. Louis presents her research on the Jun B gene from hair cells in the chicken ear as part of the Young Scientist Program at the School of Medicine.

Test can predict spread of eye cancer to liver

Gene expression mapScientists at the School of Medicine have developed a method to predict whether melanoma of the eye will spread to the liver, where it quickly turns deadly. They also believe the molecular screening test may one day help determine the prognosis of patients with some types of skin melanoma. The researchers found that a particular molecular signature — a pattern of activation of a group of genes in the tumor cells — accurately predicts risk for metastasis.

On her way

Photo by Robert BostonFirst-year medical students take part in long tradition of receiving white coats.

Pathway toward gene silencing described in plants

Olga Pontes is Going FISHin’.Biologists at Washington University in St. Louis have made an important breakthrough in understanding a pathway plant cells take to silence unwanted or extra genes using short bits of RNA. Basically, they have made it possible to see where, and how, the events in the pathway unfold within the cell, and seeing is believing, as the old saying goes. Craig Pikaard, Ph.D., Washington University professor of biology in Arts & Sciences and his collaborators have described the roles that eight proteins in Arabidopsis plants play in a pathway that brings about DNA methylation, an epigenetic function that involves a chemical modification of cytosine, one of the four chemical subunits of DNA. More…
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