School of Medicine

Surgery is the only treatment for an abdominal aortic aneurysm, a weak spot in the body’s main artery that dilates dangerously over time. If the vessel ruptures suddenly before surgery to repair it, a quick death is virtually certain. Now, scientists say they have identified a key enzyme that triggers chronic inflammation in the aorta and promotes the growth of aneurysms. Their finding raises hopes for developing a drug that could prevent small aneurysms from enlarging to the point where surgery is necessary.

DamianoPhysicians have an effective new option for treating atrial fibrillation, a common irregular heart rhythm that can cause stroke. WUSM heart surgeons under the direction of Ralph Damiano have developed and tested a device that radically shortens and simplifies a complex surgical procedure that has had the best long-term cure rate for persistent atrial fibrillation. The simplified procedure is termed Cox-maze IV, and the surgeons believe it can replace the older “cut and sew” Cox-maze III.

If you wanted to start today to reduce your chances of getting cancer, what would you have to do? Lose excess weight, get more exercise, eat a healthy diet and quit smoking. Those basic behavior changes would have a tremendous impact on the incidence of the most prevalent types of cancer — lung, breast, prostate and colon cancer — says Graham Colditz, associate director of Prevention and Control at the Siteman Cancer Center at Washington University School of Medicine in St. Louis.

MugliaAfrican-American women are three times more likely to deliver babies three to 17 weeks prematurely than Caucasian women, according to a review of Missouri birth statistics by a group of researchers headed by professor Louis Muglia. In addition, African-American women are more likely to deliver babies prematurely in subsequent pregnancies.

Photo by Robert BostonPhysicians cut the ribbon at the grand opening of the Northwest Tower, which houses faculty offices.

David J. Murray, M.D., has been named the Carol B. and Jerome T. Loeb Professor in the School of Medicine. Washington University Chancellor Mark S. Wrighton and Larry J. Shapiro, M.D., executive vice chancellor for medical affairs and dean of the School of Medicine, made the announcement.

School of Medicine researchers have developed a three-hour workshop that trains health-care providers to identify potentially unsafe drivers with dementia.

Michael T. Marrah, J.D., and Bradley J. Castanho, Ph.D., have been named assistant vice chancellors for research and co-directors of the Office of Technology Management.

A new finding by School of Medicine researchers adds a new layer of complexity to the quest to understand the causes of childhood brain cancers.

EberleinTimothy Eberlein received the 2006 Dr. Rodman L. Sheen and Thomas G. Sheen Award, given each year for outstanding contributions to the medical profession. Eberlein is Bixby Professor and chairman of the Department of Surgery, the Spencer T. and Ann W. Olin Distinguished Professor and director of the Siteman Cancer Center at the School of Medicine and surgeon-in-chief at Barnes-Jewish Hospital.