Discovery could increase tumors’ sensitivity to radiation therapy

Mouse embryos stained to show MOF (green) and its histone tag (red) demonstrate that MOF is essential for cell proliferation.To make tumors more sensitive to the killing power of radiation is a key aspiration for many radiation oncologists. Researchers at the School of Medicine have uncovered new information that leads them closer to that goal. In an upcoming issue of the journal Molecular and Cellular Biology, they report the first extensive study of an enzyme called MOF that helps control how DNA is packaged in cells. The researchers show that MOF is an essential factor for tumor development, and they say it may be possible to manipulate the enzyme to make tumors more sensitive to radiation therapy.

Immense new facility to house BioMed 21 research

The largest building ever constructed on the School of Medicine campus will be the home base for BioMed 21, the University’s innovative research initiative designed to speed scientific discovery and to rapidly apply breakthroughs to patient care.

BJC Institute of Health established at Washington University with $30 million gift

Artist’s rendering of a rooftop view of the new buildingA $30 million gift from BJC HealthCare will help construct a new 11-story research building on the campus of Washington University School of Medicine in St. Louis. This is the largest donation ever received for construction of a building at the School of Medicine. To be named the BJC Institute of Health at Washington University, the building will house the laboratories and support facilities for BioMed 21, the University’s research initiative to rapidly translate basic research findings into advances in medical treatment.

Immense new facility to house BioMed 21 research at Washington University Medical Center

Artist’s rendering of the new buildingThe largest building ever constructed on the campus of Washington University School of Medicine in St. Louis will be the home base for BioMed 21 — the University’s innovative research initiative designed to speed scientific discovery and apply breakthroughs to patient care rapidly. The building is supported by a $30 million gift to Washington University’s medical school from BJC HealthCare and will be named the BJC Institute of Health at Washington University.

Data center construction will support advances in genome sequencing

An important component of BioMed 21, the Genome Sequencing Center at Washington University in St. Louis is a gene-sequencing powerhouse and one of the four such centers in the world. It specializes in large-scale, high-throughput genome sequencing, supplying data that helps researchers at the School of Medicine identify the genetic factors that contribute to disease.
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