Children’s asthma may be prevented by blocking effects of viral infections, say WUSTL researchers

Babies who get severe respiratory viral infections are much more likely to suffer from asthma as they get older. Now School of Medicine researchers have pinpointed a key step in the development of asthma in mice after a severe respiratory infection. They suggest that medications designed to interfere with this mechanism could potentially prevent many […]

November 2007 Radio Service

Listed below are this month’s featured news stories. • Age-related macular degeneration (week of Nov. 7) • An eye on curing diabetes (week of Nov. 14) • Obesity and heart disease in kids (week of Nov. 21) • Depression and diabetes (week of Nov. 28)

Poxvirus’s ability to hide from the immune system may aid vaccine design

The cowpox virus, a much milder cousin of the deadly smallpox virus, can keep infected host cells from warning the immune system that they have been compromised, researchers at the School of Medicine have found. The scientists also showed that more virulent poxviruses, such as the strains of monkeypox prevalent in Central Africa, likely have the same ability.

Cancer gene drives pivotal decision in early brain development

A gene linked to pediatric brain tumors is an essential driver of early brain development, researchers at the School of Medicine have found. The study, published in October in Cell Stem Cell, reveals that the neurofibromatosis 1 (NF1) gene helps push stem cells down separate paths that lead them to become two major types of brain cells: support cells known as astrocytes and brain neurons.

Volunteers needed for Parkinson’s disease studies

Researchers at the School of Medicine are seeking volunteers with Parkinson’s disease for two studies. One is investigating the effects of antidepressant drugs on depression and motor function. The second study is assessing the safety and effectiveness of a drug for Parkinson’s patients who also have psychotic symptoms. In the NIH-funded depression study, investigators are evaluating paroxetine (Paxil) and venlafaxine XR (Effexor) for their success in alleviating depression and for their potential effect on motor function in Parkinson’s patients.
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