Pat on the back

Photo by Robert BostonEighteen School of Medicine faculty were recognized Jan. 23 for their accomplishments in clinical care, community service, education and research.

Assembly Series wrestles with bioethical questions

Looking back over the recent past, the advances in biomedicine seem astonishing. The birth of the first “test tube baby” 30 years ago, for example, was viewed as exotic and, to some, scary. Now, in vitro fertilization is commonplace. And yet, justifiable ethical concerns surround the human outcomes of these medical breakthroughs. Leon Kass, M.D., […]

Woman is first in region to receive new heart valve without open-heart surgery

John Lasala and Ralph Damiano Jr. work together on the first surgery in the PARTNER trial. A 78-year-old St. Louis woman was the first patient in this region to receive an experimental device to replace her defective aortic valve without opening the chest wall or using a heart-lung machine. This procedure was performed by Washington University heart specialists at Barnes-Jewish Hospital on Jan. 15.

Disrupting common parasites’ ability to “talk” to each other reduces infection

*T. gondii* imaged just after reproduction inside a host cell. (Photo by Wandy Beatty.)One of the most common human parasites, Toxoplasma gondii, uses a hormone lifted from the plant world to decide when to increase its numbers and when to remain dormant, researchers at the School of Medicine have found. The scientists report this week in Nature that they successfully blocked production of the molecule, known as abscisic acid (ABA), with a plant herbicide. Low doses of the herbicide prevented fatal T. gondii infection in mice.

Insights into cell movement likely to aid immune study, cancer research

Scientists at the School of Medicine have used yeast cells to better understand a collection of proteins associated with the formation of actin networks, which are essential to cell movement. The cell’s ability to move is important to a broad range of biomedical concerns, including understanding how immune system cells pursue disease-causing invaders and how metastasizing cancer cells migrate from a tumor.
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