Cancer gene drives pivotal decision in early brain development

A gene linked to pediatric brain tumors is an essential driver of early brain development, researchers at the School of Medicine have found. The study, published in October in Cell Stem Cell, reveals that the neurofibromatosis 1 (NF1) gene helps push stem cells down separate paths that lead them to become two major types of brain cells: support cells known as astrocytes and brain neurons.

Volunteers needed for Parkinson’s disease studies

Researchers at the School of Medicine are seeking volunteers with Parkinson’s disease for two studies. One is investigating the effects of antidepressant drugs on depression and motor function. The second study is assessing the safety and effectiveness of a drug for Parkinson’s patients who also have psychotic symptoms. In the NIH-funded depression study, investigators are evaluating paroxetine (Paxil) and venlafaxine XR (Effexor) for their success in alleviating depression and for their potential effect on motor function in Parkinson’s patients.

Great American Smokeout presents a time to quit

An estimated one million smokers will attempt to kick the habit this month as part of the annual Great American Smokeout. The Siteman Cancer Center at Washington University School of Medicine and Barnes-Jewish Hospital will offer its annual “Siteman Smokeout for Life,” Thursday, November 15 from 10 a.m. to 2 p.m. at the Center for Advanced Medicine at the corner of Euclid and Forest Park.
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