Doctors can unmask deceptive high-risk breast tumors using genetic profile

A unique genetic signature can alert physicians to high-risk breast tumors that are masquerading as low-risk tumors, according to research at the School of Medicine and collaborating institutions. Although these tumors are apparently estrogen-receptor positive — meaning they should depend on estrogen to grow — they don’t respond well to anti-estrogen therapy.

Oxygen’s impact on infection after Caesarean section studied

Researchers in the Department of Obstetrics and Gynecology are asking an old question in a new population: Can giving extra oxygen to a patient undergoing a Caesarean section (C-section) decrease the risk of serious postoperative infection? In past studies, colorectal surgery patients given supplemental oxygen had fewer infections after surgery, supporting the theory that increasing […]

Disabling mouse enzyme increases fertility

Changing the sugars attached to a hormone produced in the pituitary gland increased fertility levels in mice nearly 50 percent, a research group at the School of Medicine has found. The change appears to alter a reproductive “thermostat,” unveiling part of an intricate regulatory system that may one day be used to enhance human fertility.

Bone drug could help prevent the spread of breast cancer

Maintaining bone density could be a key to decreasing the spread of cancer in women with locally advanced breast cancer, according to research at the School of Medicine. Bones are common sites for the spread, or metastasis, of breast cancer. Scientists here found that women treated for stage II/III breast cancer who also received a bone strengthening drug were less likely to have breast tumor cells growing in their bones after three months.
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