School of Medicine

Jeffrey Bradley, associate professor of radiation oncology, has been named the first director of the Kling Center for Proton Therapy, a facility for treating cancer patients with a new, highly precise form of radiation therapy. The center is scheduled to open in summer 2009 at the Siteman Cancer Center at the School of Medicine and Barnes-Jewish Hospital.

Women born after 1944 began drinking alcohol at younger ages than their elders, and that appears to have put them at greater risk for alcoholism, according to researchers at the School of Medicine. On average, women born before 1944 began drinking at age 20. Those born after that started drinking alcohol at age 17, and they had a 50 to 80 percent greater risk for alcohol dependence, the researchers found.

StantonRichard Stanton has been named associate vice chancellor and associate dean for administration and finance at the School of Medicine. Stanton’s appointment, effective July 1, 2008, was announced by Larry J. Shapiro, M.D., executive vice chancellor for medical affairs and dean of the School of Medicine.

Researchers at Washington University in St. Louis are the first to identify two proteins responsible for mechanosensitive ion channel activities in plant roots. Scientists have long known that plant cells respond to physical forces. Until now, however, the proteins controlling the ion channel response remained a mystery.

Research is shedding new light on what happens in the brains of children and adults affected by clinical depression, anxiety disorders and schizophrenia, according to Washington University in St. Louis studies presented at a recent mental health symposium. The findings, which come as America celebrates Mental Health Awareness Month, point to new treatment options for preschool-aged children with significant clinical depression and for severely depressed adults who don’t respond to standard treatments, such as antidepressants and psychotherapy.

When patches of red, flaky and itchy skin on newborn mice led rapidly to their deaths, researchers at the School of Medicine looked for the reason why. What they found was a molecular alarm system that serves as a sentinel to monitor the integrity of skin — the body’s essential protective barrier. The fatal effects of raising this alarm in the lab mice suggests generally that certain kinds of impairments to the skin’s structure can potentially trigger harmful effects in other areas of the body, according to the researchers.

StamilioDavid M. Stamilio, M.D., has been named director of the Division of Maternal-Fetal Medicine at the School of Medicine, effective July 1. Stamilio is replacing Yoel Sadovsky, M.D., who became director of the Magee-Womens Research Institute at the University of Pittsburgh. Stamilio’s appointment was announced by George Macones, M.D., chair of the Department of Obstetrics and Gynecology.

A unique genetic signature can alert physicians to high-risk breast tumors that are masquerading as low-risk tumors, according to research at the School of Medicine and collaborating institutions. Although these tumors are apparently estrogen-receptor positive — meaning they should depend on estrogen to grow — they don’t respond well to anti-estrogen therapy.

Researchers at the School of Medicine have defined a new type of immune response that is activated in patients with severe asthma and COPD (chronic obstructive pulmonary disease). Their discovery could dramatically improve diagnosis and treatment of patients with chronic inflammatory lung disease.

Researchers in the Department of Obstetrics and Gynecology are asking an old question in a new population: Can giving extra oxygen to a patient undergoing a Caesarean section (C-section) decrease the risk of serious postoperative infection? In past studies, colorectal surgery patients given supplemental oxygen had fewer infections after surgery, supporting the theory that increasing […]