Disabling enzyme in mice increases fertility 50 percent

Changing the sugars attached to a hormone produced in the pituitary gland increased fertility levels in mice nearly 50 percent, School of Medicine research has found. The change appears to alter a reproductive thermostat, unveiling part of an intricate regulatory system that may eventually be used to enhance human fertility.

Obituary: Jermyn, 57

John William “Bill” Jermyn III, D.O., clinical instructor in the Division of Emergency Medicine, died suddenly Thursday, May 15, 2008.

Obituary: Keathley, 78

Sharon Keathley, secretary III at the Mallinckrodt Institute of Radiology who retired in 1993, died Saturday, March 8, 2008, of complications from Alzheimer’s disease at her home in St. Louis. She was 78.

‘Oh, the Places You’ll Go!’

Photo by Robert BostonJulie Gerberding, M.D., director of the U.S. Centers for Disease Control and Prevention, spoke to School of Medicine graduates at Commencement May 16, 2008, at America’s Center.

Gene variation linked to earlier onset of Alzheimer’s symptoms

GoateInvestigators at the School of Medicine have identified a genetic variation associated with an earlier age of onset in Alzheimer’s disease. Unlike genetic mutations previously linked to rare, inherited forms of early-onset Alzheimer’s disease — which can strike people as young as their 30s or 40s — these variants influence an earlier presentation of symptoms in people affected by the more common, late-onset form of the disease.
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