Scans show immune cells intercepting parasites

Researchers may have identified one of the body’s earliest responses to a group of parasites that causes illness in developing nations. In a paper published online in Public Library of Science Pathogens, scientists report that they tracked immune cells as they patrolled the second-shallowest layer of the skin in an animal model. Injections of a genetically modified form of the parasite Leishmania major caused the immune cells to turn from their patrols and move to intercept the parasites.

Manary named Helene B. Roberson Professor of Pediatrics

ManaryMark Manary has been named the Helene B. Roberson Professor of Pediatrics at the School of Medicine. “Mark Manary is an outstanding choice for the Helene B. Roberson Professor of Pediatrics,” said Chancellor Mark S. Wrighton. “Dr. Manary has developed innovative approaches to improving the lives of children in Africa. He is a credit to his field and most deserving of this generous honor supported by an endowment gift from Helene B. Roberson.”

Lung cancer vaccine to be evaluated at Siteman Cancer Center

A vaccine designed to prevent the recurrence of lung cancer is now being tested in centers around the world including the Siteman Cancer Center at the School of Medicine and Barnes-Jewish Hospital. The vaccine stimulates the immune system to destroy cells that carry a tumor-specific antigen called MAGE-A3. This antigen is not present in normal tissue but is found in several cancer types, including 35 percent to 50 percent of cases of the most common type of lung cancer, non-small cell lung cancer.
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