School of Medicine

BoyerMartin Boyer has been named the Carol B. and Jerome T. Loeb Professor in Orthopaedic Surgery at the School of Medicine. Chancellor Mark S. Wrighton and Larry J. Shapiro, executive vice chancellor for medical affairs and dean of the School of Medicine, announced the appointment.

Researchers at the School of Medicine have found a way to dress and undress Leishmania, a parasite that causes death and disfigurement in developing countries. Scientists showed that they could control the parasite’s ability to put on its carbohydrate coat, causing it to put on the whole coat, a lighter version or to forego the coat entirely.

Mice lacking the L-Fabp gene (left) don’t become obese on a high-fat diet like normal mice.Obesity and gallstones often go hand in hand. But not in mice developed at the School of Medicine. Even when these mice eat high-fat diets, they don’t get fat, but they do develop gallstones. Researchers say the findings offer clues about genetic factors related to gallstones, and they believe better understanding of those factors may one day allow physicians to monitor people at risk and even, perhaps, to intervene before gallstones become a serious problem.

HallahanDennis Hallahan has been chosen to head the Department of Radiation Oncology at the School of Medicine. Hallahan will be named the first Elizabeth H. and James S. McDonnell III Distinguished Professor in Medicine. He will also serve on the Senior Leadership Committee of the Siteman Cancer Center.

Certain characteristics of preschool-aged children at high risk for asthma could help physicians deliver more personalized and effective treatment. Researchers at the School of Medicine and five other sites nationwide found that children who showed the most improvement in days without wheezing using an inhaled corticosteroid drug were caucasian boys who had allergies and had a hospitalization or emergency department visit for asthma symptoms in the year prior to the trial.

Working with an asthma coach helps to significantly reduce hospitalizations of low-income, African-American children with asthma, results of a new, two-year study show. Researchers at the School of Medicine and the University of North Carolina at Chapel Hill worked with nearly 200 parents of children between 2-8 years old on Medicaid who had been hospitalized for asthma at St. Louis Children’s Hospital.

A drug widely used to shrink enlarged prostates has been shown to lower the risk of prostate cancer by 23 percent in men who have an increased risk of the disease, according to results of an international clinical trial presented April 27 at the American Urological Association annual meeting in Chicago.

The School of Medicine remains No. 3 among research-oriented medical schools, according to the 2010 edition of U.S. News & World Report’s “America’s Best Graduate Schools.” The rankings appear in the April 28 issue of the magazine and in an annual guidebook.

The search for the cause of an inherited form of a rare, aggressive childhood lung cancer has uncovered important information about how the cancer develops and potentially sheds light on the development of other cancers. The finding by researchers at the School of Medicine and other collaborating institutions adds the final link to the chain connecting the gene DICER1 to cancer development.

Assisted hatching, a procedure commonly thought to improve pregnancy rates during in vitro fertilization (IVF), does not affect outcomes in most women younger than 38 years old, according to researchers at the School of Medicine. The findings are available online in Fertility and Sterility.