School of Medicine

The search for the cause of an inherited form of a rare, aggressive childhood lung cancer has uncovered important information about how the cancer develops and potentially sheds light on the development of other cancers. The finding by researchers at the School of Medicine and other collaborating institutions adds the final link to the chain connecting the gene DICER1 to cancer development.

Assisted hatching, a procedure commonly thought to improve pregnancy rates during in vitro fertilization (IVF), does not affect outcomes in most women younger than 38 years old, according to researchers at the School of Medicine. The findings are available online in Fertility and Sterility.

With eight basic medical facts in hand, doctors can now estimate the risk of bleeding for a patient having a heart attack. Using clinical variables, researchers at the School of Medicine, Duke University and collaborating institutions have created a new method to estimate bleeding risk and help lessen the chances that heart attack patients will experience this common complication.

ConstantinoJohn Constantino has been named the Blanche F. Ittleson Professor of Psychiatry and Pediatrics and director of the William Greenleaf Eliot Division of Child and Adolescent Psychiatry at the School of Medicine. The appointment was announced by Charles Zorumski, the Samuel B. Guze Professor of Psychiatry, professor of neurobiology and head of the Department of Psychiatry.

A test developed by physician-scientists at the School of Medicine may help assess more quickly the ability of Alzheimer’s drugs to affect one of the possible underlying causes of Alzheimer’s disease in humans, accelerating the development of new treatments.

For years, microbiologist Stephen Beverley has tried to get the disease-causing parasite Leishmania in the mood for love. In this week’s Science, he and colleagues at the National Institutes of Health report that they may have finally found the answer: Cram enough Leishmania into the gut of an insect known as the sand fly, and the parasite will have sex.

The predominance of heartburn among asthma sufferers led many specialists to suspect that acid reflux could be a trigger for the coughing, wheezing and breathlessness of asthma. In fact, it has become standard practice to prescribe heartburn medication to people with poorly controlled asthma, even if they don’t have overt acid reflux symptoms. But a new study shows that heartburn medication does not help control asthma symptoms.

Alex A. Kane has been named the Dr. Joseph B. Kimbrough Chair for Pediatric Dentistry in the Washington University Department of Surgery, Division of Plastic Surgery for Use in the Cleft Palate/Craniofacial Deformities Institute for teaching and healing. Kane is associate professor of plastic and reconstructive surgery at the School of Medicine and director of the Cleft Palate and Craniofacial Institute at St. Louis Children’s Hospital.

The Kay Yow/Women’s Basketball Coaches Association Cancer Fund and The V Foundation announced that Michael Welch, Ph.D. and John-Stephen Tyler, Ph.D. received the first research grant awarded with money raised by the Kay Yow/WBCA Fund. Awarded during the NCAA Women’s Final Four weekend in St. Louis, Mo., the grant will fund a breast cancer research project at the Siteman Cancer Center at the School of Medicine and Barnes-Jewish Hospital.

Researchers have used socialization and mating among fruit flies to explore the connections between memory and sleep.A new theory about sleep’s benefits for the brain gets a boost from fruit flies in this week’s Science. Researchers at the School of Medicine found evidence that sleep, already recognized as a promoter of long-term memories, also helps clear room in the brain for new learning.