Brain scans show link between education, Alzheimer’s disease
School of Medicine scientists found that some patients who had brain plaques associated with Alzheimer’s disease still tested high in cognitive ability.
Sulfur and silver
Photo by Robert BostonArea high school students visited the School of Medicine for Women in Science Day, sponsored by the Young Scientist Program and the Association for Women in Science.
Previously unknown cell may help those with Crohn’s, colitis
School of Medicine researchers indicate that the immune cells could have a therapeutic role in inflammatory bowel diseases.
Worm genome offers clues to parasitism
The genome of a humble worm may provide clues to the evolution of parasitic worms, including those that infect humans, School of Medicine researchers found.
Brain implants may help stroke patients overcome partial paralysis
Scientists have shown for the first time that neuroprosthetic brain implants may be able to help stroke patients with partial paralysis.
Pain and itch responses regulated separately
Historically, scientists have regarded itching as a less intense version of the body’s response to pain, but researchers at the School of Medicine have determined that pain and itch actually are regulated by different molecular mechanisms. Researchers report they have separated itch and pain sensations in mice, a finding that could have important implications for treating both pain and chronic itching.
Cooling the brain prevents cell death in young mice exposed to anesthesia
New research from the School of Medicine suggests cooling the brain may prevent the death of nerve cells that has been observed in infant mice exposed to anesthesia. The effects of anesthesia on human infants and young children have been debated among neuroscientists, but growing evidence suggests exposure to anesthetic drugs during brain development may contribute to behavioral and developmental delays.
Drug therapy for premature infants destroys brain cells in mice
A class of drugs that are used in premature infants to treat chronic lung damage can cause damage in the brain. New research at the School of Medicine suggests the drugs may cause cognitive and motor-control problems even when they are given before birth.
Gene chips accurately detect pneumonia in ICU patients on ventilators
Even seasoned doctors have a difficult time diagnosing pneumonia in hospitalized patients breathing with the assistance of a ventilator. That’s because a patient’s underlying illness often skews laboratory test results and masks pneumonia’s symptoms. Now, researchers at the School of Medicine report they have validated the use of gene chip technology to rapidly and accurately detect pneumonia associated with ventilator use in hospitalized patients.
New gene silencing pathway found in plants
Biologists at Washington University in St. Louis have made major headway in explaining a mechanism by which plant cells silence potentially harmful genes. A team led by Craig Pikaard, Ph.D., WUSTL professor of biology in Arts & Sciences, has published a paper this month in Cell, that explains how RNA polymerases work together to use the non-coding region of DNA to prevent destructive, virus-derived genes from being activated.
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