School of Medicine

The Kay Yow/Women’s Basketball Coaches Association Cancer Fund and The V Foundation announced that Michael Welch, Ph.D. and John-Stephen Tyler, Ph.D. received the first research grant awarded with money raised by the Kay Yow/WBCA Fund. Awarded during the NCAA Women’s Final Four weekend in St. Louis, Mo., the grant will fund a breast cancer research project at the Siteman Cancer Center at the School of Medicine and Barnes-Jewish Hospital.

Researchers have used socialization and mating among fruit flies to explore the connections between memory and sleep.A new theory about sleep’s benefits for the brain gets a boost from fruit flies in this week’s Science. Researchers at the School of Medicine found evidence that sleep, already recognized as a promoter of long-term memories, also helps clear room in the brain for new learning.

A multicenter study has found two new genetic variants associated with an increased risk of breast cancer. The study was conducted by the Cancer Genetic Markers of Susceptibility (CGEMS) initiative and reported through advance online publication this week in Nature Genetics.

Patients with severe heart failure can be bridged to eventual transplant by a new, smaller and lighter implantable heart pump, according to a just-completed study of the device. Results of this third-generation heart assist device were reported at the 58th annual meeting of the American College of Cardiology on March 30.

Scientists who first established a link between obesity and the trillions of friendly microbes that live in the intestine now are investigating whether the organisms can contribute to the converse: severe malnutrition. Researchers at the School of Medicine, led by microbiologist Jeffrey Gordon, M.D., will study whether severely malnourished infants living in Malawi and Bangladesh have a different mix of intestinal microbes than healthy infants in the same areas, and whether those microbes might account for their illness. This three-year, $5.5 million project is funded by the Bill & Melinda Gates Foundation.

DehnerLouis P. “Pepper” Dehner, a faculty member at the School of Medicine, received the Distinguished Pathologist Award of the United States and Canadian Academy of Pathology (USCAP) at the academy’s 2009 annual meeting. Held in Boston March 7-13, the meeting is the largest annual gathering of pathologists, and the Distinguished Pathologist Award is its highest honor.

Funding from the Missouri Life Sciences Research Fund, part of the 1998 state tobacco settlement, will establish the St. Louis Institute of Nanomedicine Working Group, a collaborative regional effort to apply advances in nanotechnology to the treatment of human diseases.

Detectives on television shows often spray crime scenes with a compound called luminol to make blood glow. Researchers at the School of Medicine have applied the same compound to much smaller crime scenes: sites where the immune system attacks the body’s own tissues.

All animals, including humans, have an internal 24-hour clock or circadian rhythm that creates a daily oscillation of body temperature, brain activity, hormone production and metabolism. Studying mice, researchers at the School of Medicine and Northwestern University found how the biological circadian clock mechanism communicates with processes that govern aging and metabolism.

Nationally recognized StoryCorps will visit the Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine April 17-21 as part of a collaborative project to better understand how parents with cancer discuss the diagnosis with their children. This visit is the first time that StoryCorps, the largest oral history project of its kind, has partnered to collect the stories of cancer survivors on a single topic.