Young age at first drink may affect genes and risk for alcoholism
The age at which a person takes a first drink may influence genes linked to alcoholism, making the youngest drinkers the most susceptible to severe problems.
Registry to track children with infantile spasms
PaciorkowskiResearchers at the School of Medicine and the University of Chicago have launched what is believed to be the first worldwide, online registry of children with infantile spasms, a severe type of epilepsy that affects babies in the first few months of life.
Researchers find two more genetic risk factors for Alzheimer’s disease
An international team of scientists has identified two more genetic risk factors for Alzheimer’s disease. The findings are reported in the online edition of the journal Nature Genetics.
Genomics and Future of Medicine is focus of Institute of Medicine meeting
The Institute of Medicine (IOM) will host a regional meeting on Genomics and the Future of Medicine from 4 p.m. to 5:30 p.m. Sept. 10 in the Eric P. Newman Education Center at the School of Medicine.
Murray named chief of pediatric anesthesiology
MurrayDavid J. Murray has been appointed as chief of the Division of Pediatric Anesthesiology at the School of Medicine. Murray, the Carol B. and Jerome T. Loeb Professor and head of medical simulation at the School of Medicine, also becomes anesthesiologist-in-chief at St. Louis Children’s Hospital.
Fat in the liver — not the belly — is a better marker for disease risk
New findings from nutrition researchers at the School of Medicine suggest that it’s not whether body fat is stored in the belly that affects metabolic risk factors for diabetes, high blood triglycerides and cardiovascular disease, but whether it collects in the liver. They report online in the journal PNAS Early Edition that when fat collects in the liver, people experience serious metabolic problems such as insulin resistance, which affects the body’s ability to metabolize sugar.
Research shows why low vitamin D raises heart disease risks in diabetics
Low levels of vitamin D are known to nearly double the risk of cardiovascular disease in patients with diabetes, and now researchers at the School of Medicine think they know why. They have found that diabetics deficient in vitamin D can’t process cholesterol normally, so it builds up in their blood vessels, increasing the risk of heart attack and stroke.
Low-dose estrogen shown safe and effective for metastatic breast cancer
When estrogen-lowering drugs no longer control metastatic breast cancer, the opposite strategy might work. Raising estrogen levels benefited 30 percent of women whose metastatic breast cancer no longer responded to standard anti-estrogen treatment, according to research conducted at the School of Medicine and collaborating institutions.
Scientists identify cells in fruit fly gut that start tumors
Tumor growth can start from stem cells in the gut, say researchers studying fruit flies at the School of Medicine. They found that tumors can grow from adult stem cells that have lost a specific tumor-suppressor gene. The gene, Apc, has previously been implicated in human gastrointestinal cancers, including colon cancer.
Sleckman named Conan Professor of Laboratory and Genomic Medicine
SleckmanBarry P. Sleckman has been named the Conan Professor of Laboratory and Genomic Medicine at the School of Medicine. Washington University Chancellor Mark S. Wrighton and Larry Shapiro executive vice chancellor for medical affairs and dean of the School of Medicine, announced the appointment.
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