Protein helps parasite survive in host cells

Researchers at Washington University School of Medicine in St. Louis have learned why changes in a single gene, ROP18, contribute substantially to dangerous forms of the parasite Toxoplasma gondii. The answer has likely moved science a step closer to new ways to beat Toxoplasma and many other parasites.

New model will open immune cell’s secrets

Five decades after the discovery of a rare but potentially pivotal immune cell, scientists at Washington University School of Medicine in St. Louis have found a way to eliminate it in mice. The finding, which appears in the journal Immunity, will enable more detailed investigations of the important roles the plasmacytoid dendritic cell (pDC) plays in fighting viruses and causing autoimmune diseases like psoriasis and lupus.

PSA test better predicts cancer in men taking prostate-shrinking drug

A new study by Gerald Andriole, MD, chief of urologic surgery at Washington University School of Medicine in St. Louis, suggests the PSA test is more reliable in men taking dutasteride (Avodart®), a drug widely prescribed to shrink an enlarged prostate gland. Even a slight rise in PSA levels among men taking the drug was a stronger indicator of cancer than rising PSA levels in men taking a dummy pill.

Emerson, AT&T give $7.5 million to Siteman Cancer Center

Innovative, high-priority research initiatives by Washington University scientists at the Alvin J. Siteman Cancer Center are now under way thanks to a $7.5 million grant from Emerson and AT&T. Emerson’s Charitable Trust and the AT&T Foundation are contributing $5 million and $2.5 million, respectively. This commitment will generate an additional $15 million for these initiatives through matching support from Washington University School of Medicine, BJC HealthCare and the Siteman Cancer Center.
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