School of Medicine

In the first large trial of its kind in the United States, researchers have shown that estrogen-lowering drugs can shrink tumors and reduce mastectomy rates for patients with stage 2 or 3 breast cancer.

A protein that helps the brain develop early in life can fight the mental fuzziness induced by sleep deprivation, according to Paul Shaw, PhD, a researcher at Washington University School of Medicine in St. Louis.

Youngjee Choi’s undergraduate degrees in psychology and philosophy–neuroscience–psychology paired with summer research experiences prepared her well for her interest in academic medicine. Choi will graduate May 20 with a medical degree from the School of Medicine.

Walter F. Ballinger II, MD, former head of the Department of Surgery at Washington University School of Medicine, died Friday, April 29, 2011, of pneumonia at Barnes-Jewish Hospital. He was 85.

Erik Trinkaus, PhD, considered by many to be the world’s most influential scholar of Neandertal and early modern human biology and evolution, and Wayne M. Yokoyama, MD, an internationally renowned immunologist and arthritis researcher, will receive Washington University’s 2011 faculty achievement awards, Chancellor Mark S. Wrighton announced.

Higher levels of cellular chatter boosts levels of amyloid beta in the brain regions that Alzheimer’s hits first, researchers at Washington University School of Medicine in St. Louis report. Amyloid beta is the main ingredient of the plaque lesions that are a hallmark of Alzheimer’s. The finding may help explain why areas that are most active when the brain rests are often among the first to develop these plaques, according to the researchers.

At 37, Eric Leuthardt, MD, assistant professor of neurosurgery, is No. 5 on a list of the world’s 100 most prolific patent holders. He posts entries to his blog, Brains and Machines, on Tumblr about general brain science and his own work as a surgeon, teacher, researcher and inventor. He directs the Center for Innovation in Neuroscience and Technology, and he has just sent drafts of his first novel to prospective publishers.

To kick off a new Styrofoam recycling program at the School of Medicine this month, members of about 15 labs in the Department of Molecular Microbiology loaded one-year’s worth of Styrofoam into a 52-foot 18-wheeler truck April 28. Employees spent one hour loading the Styrofoam into the truck, which was filled about halfway.

Both the Danforth and Medical campuses at WUSTL held many events to celebrate the week of Earth Day April 18-23. At the Medical Campus, Courtney Pike and Liz Wright talk to Changguo Tang, PhD, about gardening and water conservation in front of the BJC Institute of Health at Washington University School of Medicine April 20.

Paul R. Manske, MD, professor of orthopaedic surgery, died Wednesday, April 20, 2011, at Barnes-Jewish Hospital of an extended illness. He was 72. Manske, a hand surgeon at Washington University since the late 1960s, was chairman of the Division of Orthopaedic Surgery from 1983-1995. In addition, he was formerly orthopedic surgeon in chief at Barnes Hospital and director of hand surgery at Shriner’s Hospital for Children.