The biology behind alcohol-induced blackouts

Neuroscientists at Washington University School of Medicine in St. Louis have identified the brain cells involved in alcohol-related blackouts and the molecular mechanism that appears to underlie them. Alcohol interferes with key receptors in the brain, which in turn manufacture steroids that inhibit long-term potentiation, a process that strengthens the connections between neurons and is crucial to learning and memory. 

Surprising culprits behind cell death from fat and sugar overload

Excess nutrients, such as fat and sugar, don’t just pack on the pounds but can push some cells in the body over the brink. Unable to tolerate this “toxic” environment, these cells commit suicide. Now, scientists at Washington University School of Medicine in St. Louis have discovered three unexpected players that help a cell overloaded with fat initiate its own demise.

New procedure treats atrial fibrillation

Doctors at Washington University School of Medicine in St. Louis are performing a new procedure to treat atrial fibrillation, a common irregular heartbeat. Available at only a handful of U.S. medical centers, this “hybrid” procedure combines minimally invasive surgical techniques with the latest advances in catheter ablation. The two-pronged approach gives doctors access to both the inside and outside of the heart at the same time, helping to more completely block the erratic electrical signals that cause atrial fibrillation.
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