Brain abnormalities seen in children with severe form of diabetes

Children with a rare syndrome that includes a form of insulin-dependent diabetes have brain abnormalities that appear to set the stage for cognitive problems later in life, according to new research at Washington University School of Medicine in St. Louis. Scientists, including Tamara Hershey, PhD, had assumed those brain changes occurred late in the disease process, but the new findings suggest that some changes occur early in childhood.

Urinary tract infections steal from hosts’ defense arsenals

Humans have known for centuries that copper is a potent weapon against infection. New research shows that the bacteria that cause serious urinary tract infections “know” this, too, and steal copper to prevent the metal from being used against them. Blocking this thievery with a drug may significantly improve patients’ chances of fighting off infections, according to researchers.

Surprising culprit behind chemo resistance in rare cancer

Researchers led by Michael H. Tomasson, MD, at Washington University School of Medicine in St. Louis have shown how an aggressive form of multiple myeloma resists chemotherapy. Multiple myeloma is a rare cancer of plasma cells in the bone marrow. Though the finding has no immediate benefit for patients, the scientists say it could help guide research into better treatments.

Bhutanese cardiologist adds techniques to take home

Victor Davila-Roman, MD, professor of medicine; and Yeshey Penjose, MD, a cardiologist from the National Referral Hospital in Thimpu, Bhutan, study a sonogram of a heart at the Center for Advanced Medicine. Penjose was training in echocardiography at the School of Medicine for two months as part of the Global Health Scholars Program.
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