School of Medicine

Patients and staff in several Barnes-Jewish Hospital resident clinics began moving into the 12-story Center for Outpatient Health at the corner of Forest Park and Euclid avenues March 12. Many of the clinics will be relocated by the end of March, with all moves complete by the end of spring.

Fourth-year students at Washington University School of Medicine, including Kevin Choong and Julietta Chang, learned March 16 where they will continue their medical training. This year, 121 students matched to internships or residencies nationwide and in Canada.

A new drug makes chemotherapy more effective in treating acute myeloid leukemia, a cancer of the white blood cells, according to John F. DiPersio, MD, PhD, and his colleagues at Washington University. Instead of attacking these cells directly, the drug helps drive them out of the bone marrow and into the bloodstream, where they are more vulnerable to chemotherapy.

Postdoctoral researchers will showcase their work at the 8th Annual Postdoc Scientific Symposium at Washington University School of Medicine in St. Louis. The symposium will be held from 11:30 a.m.-5:30 p.m., March 29, 2012, at the Farrell Learning and Teaching Center Atrium and Connor Auditorium.

Batten disease is a rare but fatal neurological disorder that typically strikes young children. Working in mice with the infantile form of the disease, scientists have discovered dramatic improvements in life span and motor function by treating the animals with gene therapy and bone marrow transplantation.

By mapping the evolution of cancer cells in patients with myelodysplastic syndromes who later died of leukemia, Timothy Graubert, Matthew Walter and their Washington University colleagues have found clues to suggest that targeted cancer drugs should be aimed at mutations that develop early in the disease.

With every meal, immune cells in the intestine stand like sentries at a citadel, turning away harmful bacteria but allowing vitamins and nutrients to pass. Now, researchers at Washington University School of Medicine in St. Louis have identified the cells that chaperone food antigens, or proteins, in the intestine so that the immune system doesn’t mount an attack. Their discovery provides scientists with a potential target for therapies against inflammatory bowel disease, celiac disease and food allergies.

Louis W. Sullivan, MD, secretary of the Department of Health and Human Services in the administration of President George H. W. Bush and president emeritus of the Morehouse School of Medicine, will lead a public forum on the future of health care at 4 p.m. Wednesday, April 11, at the Eric P. Newman Education Center, 320 S. Euclid Ave., at Washington University School of Medicine in St. Louis.

Researchers, including Richard Wilson, PhD, director of The Genome Institute, have identified the first gene mutation associated with a chronic and often fatal form of neuroblastoma that typically strikes adolescents and young adults. The finding provides the first clue about the genetic basis of the long-recognized but poorly understood link between treatment outcome and age at diagnosis.

A program that helps obese patients improve healthy behaviors is associated with modest weight loss and improved blood pressure control in a high-risk, low-income group, according to Graham A. Colditz, MD, DrPH, at Washington University School of Medicine. Compared to those receiving usual care, the lifestyle intervention slowed increases in weight and blood pressure in this population of high-risk patients.