Soil bacteria and pathogens share antibiotic resistance genes

Disease-causing bacteria’s efforts to resist antibiotics may get help from their distant bacterial relatives that live in the soil, new research by Kevin Forsberg, a graduate student at Washington University School of Medicine suggests. The researchers found identical genes for antibiotic resistance in soil bacteria and in pathogens from clinics around the world.

Washington People: Randall Bateman

Randall Bateman, MD, had no intention of becoming a doctor when he enrolled as an undergraduate at Washington University in St. Louis. As a faculty member at the School of Medicine since 2006, Bateman now focuses his research on Alzheimer’s disease.

Brain differences seen at 6 months in infants who develop autism

Researchers have found significant differences in brain development in infants as young as six months old who later develop autism, compared to babies who don’t develop the disorder. The new research, which relied on brain scans acquired at night while infants were naturally sleeping, suggests that autism doesn’t appear abruptly, but instead develops over time during infancy.

Celebrating community spirit

Brian Phillips; Larry J. Shapiro, MD, executive vice chancellor for medical affairs and dean of the School of Medicine; and Joseph Roddy, St. Louis Alderman for the 17th Ward, celebrate after Roddy presented Shapiro with a proclamation thanking the School of Medicine for its Holiday Outreach program, orchestrated by the Washington University Medical Center Redevelopment Corp.

Diabetes may start in the intestines, research suggests

Scientists at Washington University School of Medicine in St. Louis have made a surprising discovery about the origin of diabetes. Their research suggests that problems controlling blood sugar — the hallmark of diabetes — may begin in the intestines. The new study, in mice, may upend long-held theories about the causes of the disease.

Combination PET-MRI scanner expands imaging frontiers

p, , {margin:0in;margin-bottom:.0001pt;font-size:12.0pt;font-family:Cambria;} .t {font-size:10.0pt;font-family:Cambria;} @page WordSection1 {size:8.5in 11.0in;margin:1.0in 1.25in 1.0in 1.25in;} div.WordSection1 {page:WordSection1;} Scientists at Washington University School of Medicine are using a new imaging device that simultaneously performs positron-emission tomography (PET) and magnetic resonance imaging (MRI) scans, producing more detailed images than either technique alone. The scanner’s power and versatility will enable many wonderful applications in areas ranging from cancer to neurological disorders to heart and lung disease.

Autism affects motor skills, study indicates

Children with autism often have problems developing motor skills, such as running, throwing a ball or even learning how to write. But scientists have not known whether those difficulties run in families or are linked to autism. New research at Washington University School of Medicine in St. Louis by Claudia List Hilton, PhD, points to autism as the culprit.

Antibiotics ineffective for most sinus infections

Antibiotics that doctors typically prescribe for sinus infections do not reduce symptoms any better than an inactive placebo, according to Jay F. Piccirillo, MD, and his co-investigators at Washington University School of Medicine in St. Louis. Instead of giving antibiotics, the researchers suggest treating symptoms, such as pain, cough and congestion, along with watchful waiting to see whether further treatment is necessary.

Protein may play role in obesity, diabetes, aging

Researchers at Washington University School of Medicine in St. Louis, led by Philip Stahl, PhD, professor of cell biology and physiology have identified a potent regulator of sensitivity to insulin, the hormone that controls blood sugar levels. The new findings may help scientists find better treatments for type 2 diabetes, obesity and other health problems caused by the body’s inability to properly regulate blood sugar.
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