School of Medicine

Washington University in St. Louis has awarded five Bear Cub fund grants totaling $190,000 to support innovative research that has shown commercial potential. Jerry Morrissey (right), PhD, received one of the grants to develop rapid tests for the early development of kidney cancer.

New research from Washington University School of Medicine in St. Louis shows that the same genes that promote healing after cartilage damage also appear to protect against osteoarthritis, a condition caused by years of wear-and-tear on the cartilage between joints. Although the research was conducted in mice, the genes are likely to be important in people, too.

Susan E. Mackinnon, MD, received the Clinician of the Year award and the Research Achievement Award in Basic Science at the American Association of Plastic Surgeons’ annual meeting April 14-17, 2012, in San Francisco.

The Advisory Committee for the Diversity and Inclusion Grants has awarded eight grants totaling nearly $174,000 to Washington University faculty and administrators for initiatives that improve the university environment for women and members of underrepresented minority groups.

Jim Jackson (left), project manager in Facilities Management at the School of Medicine, explains energy used in light bulbs to a visitor to the energy conservation and alternative energy station at the School of Medicine’s Earth Day festivities April 19 in the BJC Institute of Health Hope Plaza. In addition to energy, visitors learned about recycling, gardening and water conservation, and transportation and clean air.

David M. Jaffe, MD, was elected president of the Academic Pediatric Association at its recent annual meeting in Boston. Jaffe is the Dana Brown Professor of Pediatrics and director of the Division of Emergency Medicine in the Department of Pediatrics at Washington University School of Medicine in St. Louis and medical director of emergency services at St. Louis Children’s Hospital.

Charged atoms, or ions, move through tiny pores, or channels, embedded in cell membranes, generating the electrical signals that allow cells to communicate with one another. In new research, scientists have shown how an unusual protein plays a key role in temporarily blocking the movement of ions through these channels. Preventing ions from moving through the channel gives cells time to recharge so that they can continue firing.

David Warren, MD, medical director for infection control at the School of Medicine and Barnes-Jewish Hospital, works diligently to prevent infections, but when they do occur, he pulls out all the stops to halt their spread. And in a world that is increasingly interconnected, Warren also must keep abreast of emerging global epidemics that have the potential to wreak havoc if there’s a local outbreak.

Scientists have identified the first gene directly linked to the most common form of psoriasis, a chronic skin condition. The research shows that rare mutations in the CARD14 gene, when activated by an environmental trigger, can lead to plaque psoriasis. This type of psoriasis accounts for 80 percent of all cases.

Scientists studying the way Alzheimer’s disease takes root in the brain have identified important new similarities between a mouse model and human Alzheimer’s. Researchers at Washington University School of Medicine in St. Louis have shown that brain plaques in mice are associated with disruption of the ability of brain regions to network with each other.