First detailed timeline established for brain’s descent into Alzheimer’s

Scientists have assembled the most detailed chronology to date of the human brain’s long, slow slide into full-blown Alzheimer’s disease. Through an international research partnership known as the Dominantly Inherited Alzheimer’s Network (DIAN), scientists at Washington University and elsewhere evaluated pre-symptomatic markers of Alzheimer’s disease in subjects from families genetically predisposed to develop the disorder.

Brain abnormalities seen in children with severe form of diabetes

Children with a rare syndrome that includes a form of insulin-dependent diabetes have brain abnormalities that appear to set the stage for cognitive problems later in life, according to new research at Washington University School of Medicine in St. Louis. Scientists, including Tamara Hershey, PhD, had assumed those brain changes occurred late in the disease process, but the new findings suggest that some changes occur early in childhood.

Urinary tract infections steal from hosts’ defense arsenals

Humans have known for centuries that copper is a potent weapon against infection. New research shows that the bacteria that cause serious urinary tract infections “know” this, too, and steal copper to prevent the metal from being used against them. Blocking this thievery with a drug may significantly improve patients’ chances of fighting off infections, according to researchers.
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