School of Medicine

Two scientists at Washington University have developed a low-energy defibrillation scheme that significantly reduces the energy needed to re-establish a normal rhythm in the heart’s main chambers. They hope this electrotherapy will be much less painful than the existing electrotherapy, making treatment with a defibrillator much more acceptable to patients.

People with diabetes often develop clogged arteries that cause heart disease. New research at Washington University School of Medicine in St. Louis has found that when vitamin D levels are adequate in people with diabetes, blood vessels are less likely to clog. But in patients with insufficient vitamin D, immune cells bind to blood vessels near the heart, then trap cholesterol to block those blood vessels.

The School of Medicine has received a $50 million grant to help speed the translation of scientific discoveries into improvements in human health. The grant supports the School of Medicine’s Institute of Clinical and Translational Sciences, led by Bradley A. Evanoff, MD.

The region’s first maternal-fetal transport service that includes both obstetrics and pediatrics expertise is being launched this month by the School of Medicine and St. Louis Children’s and Barnes-Jewish hospitals.

Researchers have identified a genetic error responsible for some cases of a rare childhood leukemia with a poor prognosis.

Studying premature babies prior to their release from the NICU, researchers at Washington University School of Medicine in St. Louis have identified developmental differences between those preemies and babies born at full term. Their work points to opportunities for therapeutic interventions — even in the first few weeks of life — that might improve long-term outcomes for the preemies.

Researchers at Washington University School of Medicine in St. Louis have received a $9 million grant to investigate blood-clotting disorders. From heart attacks and strokes to uncontrolled bleeding, clotting disorders cause more deaths each year in the United States than all types of cancer combined.

Some students enrolled in the Cognitive, Computational and Systems Neuroscience (CCSN) pathway, are sharing their love of science and improving communication skills through community outreach. CCSN is a specialization for graduate students in psychology, neuroscience and biomedical engineering. The students are coaching low-income area teens for an international competition called the Brain Bee, and participating in many events, including the Nov. 10 Amazing Brain Carnival held at the St. Louis Science Center. The free event introduces the public to brain science research in St. Louis. 

The medical school’s Student Arts Commission is hosting a “Coffee House Concert” from 5:15-7 p.m. Thursday, Nov. 29, in the second floor atrium of the Farrell Learning and Teaching Center. The concert showcases students’ musical and performance talents.

Investigators at Washington University and The Scripps Research Institute have announced the launch of a “Global Metabolomic Initiative” to facilitate meta-analyses on studies of the metabolism of bacteria, yeast, plants, animals and people. Although metabolomics has existed as a discipline for only a decade, it has already provided insights into many difficult-to-treat diseases, including chronic pain. Many more are expected to fall out of the meta-analyses.