Discovery helps show how breast cancer spreads

School of Medicine researchers have discovered why breast cancer patients with dense breasts are more likely than others to develop aggressive tumors that spread. The finding opens the door to drug treatments that prevent metastasis. Shown are collagen fibers at the boundary of a tumor. Fibers that tend to be perpendicular to the tumor’s surface indicate a poor prognosis.

Unusual comparison nets new sleep loss marker

Paul Shaw, PhD, a researcher at the School of Medicine, has used what he learns in fruit flies to look for markers of sleep loss in humans. But now he has reversed the process in a new paper, taking what he finds in humans back to the flies and identifying a human gene that is more active after sleep deprivation.

Gelberman, Wertsch to receive 2013 faculty achievement awards

Richard H. Gelberman, MD, a world-renowned expert in hand and wrist microsurgery, and James V. Wertsch, PhD, founding director of one of the most successful and innovative global scholarship programs in the world, will receive Washington University’s 2013 faculty achievement awards, Chancellor Mark S. Wrighton announced. They will receive their awards and give presentations of their scholarly work during a Dec. 7 program.

Scientists assemble genetic playbook for acute leukemia

A consortium of researchers led by the School of Medicine has identified virtually all of the major mutations that drive acute myeloid leukemia (AML), a fast-growing blood cancer in adults that often is difficult to treat. The dark lines in the image pictured show all of the major mutations for AML that occurred in one patient with the disease.
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